Sleep Disorder in Inflammatory Bowel Disease and Its Association With Disease Activity

Prevalence of Sleep Disorder in Inflammatory Bowel Disease and Its Association With Disease Activity

Recently, an association between active inflammatory bowel disease (IBD) and poor sleep quality has been proposed; however, the causal relationship has not yet been established. This study aimed to investigate prevalence of poor sleep quality in IBD and association with disease activity by subjective and objective measures.

Prospective observational study is conducted with expected sample size of 100 patients. Participants are classified into active and inactive disease status according to standard IBD severity assessment measures. Demographic data, disease activity, quality of life, sleep questionnaire (validated PSQI questionaire), and seven-day sleep data acquired from ambulatory wrist actigraphy were obtained. Association between sleep quality and disease activity will be analyzed.

Inclusion Criteria:

• Age ≥ 18 years
• Diagnosed inflammatory bowel disease, followed up in Siriraj hospital, Mahidol University

Exclusion Criteria:

• Unstable medical conditions
• Known psychiatric disease
• Patients who could not withhold sedative drugs
• Pregnant patients
• Obese patients with body mass index (BMI) ≥ 35 kg/m2
• Refuse to sign a consent/ had cognitive impairment