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To use PSA levels after bipolar and monopolar transurethral resection of the benign prostatic hyperplasia as an indicator of the quality of resection .
PSA is a protein produced from the prostate epithelium and secreted in semen in huge amounts , small amount find its way to the circulation ,its function is to allow mobility of the sperms by interacting with the Semenogelin . clinical BPH can be defined as prostate adenoma/adenomata, causing a varying degree of BOO, which may eventually cause harm to the patients ,Treatment of this condition varies from conservative, medical and surgical depending on factors related to the patient and the surgeon preference . The early reports of minimally invasive treatment of the prostate dated back to 1937, since then and remarkable development is noticed . TURP is the golden treatment in the BPH . Studies compare between the methods according the blood transfusion , operation time retention after catheter removal , urethral complications , TUR syndrome and hospital-stay which show that bipolar is better. To our knowledge after few studies compare between the techniques according PSA also these studies show weakness in their statistically analysis with no difference between the methods .investigators aim is to study the effect of the operations on PSA levels as an indicator of the quality of resection.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bipolar TURP | Active Comparator | Patients thats will undergo bipolar TURP |
|
| Monopolar TURP | Active Comparator | Patients thats will undergo monopolar TURP |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TURP | Procedure | Bipolar and monopolar transurethral resection of the benign prostatic hyperplasia |
|
| Measure | Description | Time Frame |
|---|---|---|
| serum PSA changes after bipolar and monopolar transurethral resection of the benign prostatic hyperplasia | To use PSA levels changes after both techniques (bipolar and monopolar transurethral resection of the benign prostatic hyperplasia)as an indicator of the quality of resection | within one month after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| International Prostate Symptom Score | International Prostate Symptom Score after bipolar and monopolar transurethral resection of the benign prostatic hyperplasia | within one month after intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Andrew H Wahba Gerges, Resident doctor | Contact | +201015349430 | 01287793663 | androwhamam1234@gmail.com |
| Mahmoud M Shalaby, professor | Contact | +201111222203 | shalabymm@aun.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Mohamed A Elgamal, professor | Assiut University | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21802121 | Result | Geavlete B, Georgescu D, Multescu R, Stanescu F, Jecu M, Geavlete P. Bipolar plasma vaporization vs monopolar and bipolar TURP-A prospective, randomized, long-term comparison. Urology. 2011 Oct;78(4):930-5. doi: 10.1016/j.urology.2011.03.072. Epub 2011 Jul 29. | |
| 23703547 | Result | Pahwa M, Pahwa M, Pahwa AR, Girotra M, Chawla A, Sharma A. Changes in S-PSA after transurethral resection of prostate and its correlation to postoperative outcome. Int Urol Nephrol. 2013 Aug;45(4):943-9. doi: 10.1007/s11255-013-0474-3. Epub 2013 May 24. |
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| ID | Term |
|---|---|
| D020728 | Transurethral Resection of Prostate |
| ID | Term |
|---|---|
| D011468 | Prostatectomy |
| D013521 | Urologic Surgical Procedures, Male |
| D013520 | Urologic Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
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| D013514 | Surgical Procedures, Operative |