Transurethral Prostate Resection (TURP) vs. Prostate Artery Embolization (PAE)

Transurethral Prostate Resection (TURP) vs. Prostate Artery Embolization (PAE): Open Multicentric Randomized Study for Evaluation of Outcomes, Complications, and Health Economics

This study focuses on the treatment of benign prostatic hyperplasia which causes lower urinary tract symptoms.

The purpose of the research project is to evaluate PAE in terms of both medical and health economic outcomes. To evaluate whether there are any differences in effect (IPSS), complications, costs and perceived quality of life compared with TUR-P.

Inclusion Criteria:

• Benign prostatic hyperplasia where medical treatment has not helped or for other reasons has not been deemed applicable
• IPSS>=8
• Prostate volume [40-80] ml measured via transrectal ultrasound
• Peak flow rate (Qmax) <= 15 ml / s,
• Verified obstruction by urodynamic studies (cystometry)
• Surgery not contraindicated

Exclusion Criteria:

• Prostate cancer
• Severe atherosclerosis
• Kidney failure
• Urethral stricture
• Active cystitis or prostatitis
• Bladder stone.
• Neurogenic bladder disorder
• Contrast product allergy