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Acute septic arthritis is a rare but life-threatening and functionally serious disease. The improvement or disappearance of pain and functional recovery are sometimes difficult to obtain, with in some cases the persistence of synovitis due to a prolonged local inflammatory response, despite early and effective treatment. The consequences are significant for patients with often significant chronic pain, repercussions on autonomy and/or profession. An unfavorable evolution with joint destruction and need for replacement by a prosthesis is not uncommon.
Corticosteroid therapy is widely used in rheumatology in similar tables, for the purpose of drug synovectomy, with good results. The risk of infection remains the main contraindication to its use.
There are very few studies on its use in septic arthritis, either fundamentally or in humans, for which there are no data in adults. However, these have shown results encouraging the investigators not to neglect this therapy.
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| Measure | Description | Time Frame |
|---|---|---|
| Complete regression of the pain in a fast way | 6 months after treatment with corticosteroids |
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Inclusion criteria:
Exclusion criteria:
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Adult patient (≥18 years old) having presented with septic arthritis and treated at the Strasbourg University Hospital between January 1, 2012 and December 31, 2021
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jeannot GAUDIAS, MD | Contact | 33 3 68 76 50 64 | jeannot.gaudias@chru-strasbourg.fr | |
| Saïd CHAYER, PhD, HDR | Contact | said.chayer@chru-strasbourg.fr |
| Name | Affiliation | Role |
|---|---|---|
| Jeannot GAUDIAS, MD | Service de Chirurgie Orthopédique Septique - CHU de Strasbourg - France | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Chirurgie Orthopédique Septique - CHU de Strasbourg - France | Recruiting | Strasbourg | 67091 | France |
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| ID | Term |
|---|---|
| D001170 | Arthritis, Infectious |
| D013585 | Synovitis |
| ID | Term |
|---|---|
| D007239 | Infections |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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