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| Name | Class |
|---|---|
| United States Department of Defense | FED |
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The aim of this study is to evaluate how different combinations of prebiotics and polyphenols affect the gut microbiota and perceived cognitive state. 40 volunteers will take part in this study who will be randomised into 4 different groups. One group will consume a placebo, whereas the other groups will consume prebiotics, polyphenols, or a combination of the two.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Polyphenol | Experimental | Consume polyphenol combination for two weeks |
|
| Prebiotic | Experimental | Consume prebiotic combination for two weeks |
|
| prebiotic and polyphenol | Experimental | Combination of prebiotics and polyphenols for two weeks |
|
| Placebo | Placebo Comparator | maltodextrin placebo for two weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blueberry, cranberry, green tea extract, cocoa | Dietary Supplement | tablet supplements, available readily. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Bacteriology | Changes in bacteriology | baseline, pre-intervention, then After 14 days of intervention |
| Mood Questionnaires | various mood questionnaires | baseline, pre-intervention, then After 14 days of intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure | Blood pressure taken systolic, diastolic and pulse | baseline, pre-intervention, then After 14 days of intervention. at least three times per week also |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Reading | Reading | Berkshire | rg66dz | United Kingdom |
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| ID | Term |
|---|---|
| D013315 | Stress, Psychological |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| C000721609 | blueberry extract |
| D013662 | Tea |
| D000069956 | Chocolate |
| D007444 | Inulin |
| D056692 | Prebiotics |
| D059808 | Polyphenols |
| C008315 | maltodextrin |
| ID | Term |
|---|---|
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
| D001628 | Beverages |
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| GOS, Inulin, RS2 | Dietary Supplement | Prebiotic combination, Inulin, GOS and RS2 |
|
| prebiotics and polyphenols | Dietary Supplement | combination of the same prebiotics and polyphenols as above |
|
| Maltodextrin | Dietary Supplement | maltodextrin, 10g per day |
|
| D000066888 |
| Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
| D005502 | Food |
| D013213 | Starch |
| D005936 | Glucans |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
| D004040 | Dietary Carbohydrates |
| D002241 | Carbohydrates |
| D005630 | Fructans |
| D011134 | Polysaccharides |
| D004043 | Dietary Fiber |
| D011135 | Polysaccharides, Bacterial |
| D019587 | Dietary Supplements |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |