Phenotyping and Genotyping of Duffy Antigen

Phenotyping and Genotyping of Duffy Antigen

Malaria remains the world's leading parasitic endemic. Almost half of the world's population lives in endemic areas. Many at-risk people in African countries remain without access to malaria control. Malaria kills approximately 400,000 people each year, most of whom are children under the age of 5 in Africa. Since 2005, an increasing number of Plasmodium vivax infections have been observed in Duffy-negative populations in South America and Africa, calling into question the essential role of the PvDBP-DARC interaction. The objective of the investigators is therefore to study and understand the invasion pathways used by Plasmodium vivax in Duffy-negative subjects.

Inclusion Criteria:

• Major subjects
• with malaria and willing to have their blood samples analyzed for this research

Exclusion Criteria:

• Subjects refusing to participate in the study