A Study to Evaluate the Relative Bioavailability of Formulations of CKD-510 and to Assess the Effect of Food on the CKD-510 Tablet Formulation in Healthy Subjects

A Randomized, Open-Label, Crossover Study to Evaluate the Relative Bioavailability of a Tablet Formulation of CKD-510 as Compared to Capsule and to Assess the Effect of Food on the CKD 510 Tablet Formulation in Healthy Subjects

The purpose of this study is to determine the relative bioavailability of CKD-510 tablet formulation compared with CKD-510 capsule formulation, and to characterize the effect of food on the CKD-510 tablet.

Inclusion Criteria:

• Healthy adult male or female subject between 18 and 60 years of age
• In generally good health, based upon medical/surgical history and the results of physical examination, vital signs, safety laboratory assessments, and 12-lead ECG
• Body mass index (BMI) between 18 and 32 kg/m2
• If a female subject of childbearing potential, agrees to use a highly effective method of contraception during study participation and for 90 days after the last administration of study drug.
• If a male subject with a female partner of childbearing potential, is surgically sterile or agrees to use a highly effective method of contraception during study participation and for 90 days after the last administration of study drug
• Negative test result for SARS-CoV-2

Exclusion Criteria:

• Evidence of clinically significant hematologic, renal, endocrine, pulmonary, cardiac, gastrointestinal, hepatic, psychiatric, neurologic, immunologic, or allergic disease or any other condition
• Any hypersensitivity or allergy to CKD-510 or its excipients or to any medicinal products with similar chemical structures
• History of malignancy, other than successfully treated basal cell or squamous cell skin cancer
• History or presence of an abnormal 12-lead ECG
• Acute illness considered clinically significant by the Investigator within 30 days prior to Randomization
• Any other investigational drug within 30 days or 5 half-lives of the drug (whichever is longer) prior to Randomization