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| Name | Class |
|---|---|
| The First Affiliated Hospital of Xiamen University | OTHER |
| Zhangzhou Affiliated Hospital of Fujian Medical University | OTHER |
| Quanzhou First Hospital | OTHER |
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To compare the efficacy of two different dosage regimens of intravenous immune globulin (IVIG) in the treatment of children with newly diagnosed immune thrombocytopenia, and to reduce related adverse reactions and economic burdens on the premise of ensuring the remission rate
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| low-dose intravenous immunoglobulin | Experimental | 0.4g/kg.d, d1-5 |
|
| high-dose intravenous immunoglobulin | Active Comparator | 1.0g/kg.d, d1-2 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| intravenous immunoglobulin | Drug | To compare the efficacy of two different dosage regimens of intravenous immune globulin (IVIG) in the treatment of children with newly diagnosed immune thrombocytopenia |
| Measure | Description | Time Frame |
|---|---|---|
| early response to treatment | Platelet counts after 7 days of IVIG treatment | 7 days after treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Economic Indicators | Calculate the total amount of IVIG used in 1 week (weight normalized) | 1 week |
| Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability] | Incidence of Treatment-Emergent Adverse Events in 1 week |
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Inclusion Criteria:Subjects enrolled in this study must meet all of the following criteria:
Exclusion Criteria:Anyone who has any of the following conditions will not enter the clinical study:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Shaohua Le, Master's degree | Contact | 8613365917129 | lele883@sina.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Children with newly dignosed ITP | Recruiting | Fuzhou | Fujian | 350001 | China |
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| ID | Term |
|---|---|
| D016756 | Immunoglobulins, Intravenous |
| ID | Term |
|---|---|
| D007074 | Immunoglobulin G |
| D007132 | Immunoglobulin Isotypes |
| D000906 | Antibodies |
| D007136 | Immunoglobulins |
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| Nanping First Hospital Affiliated to Fujian Medical University |
| UNKNOWN |
| The Second Hospital of Anhui Medical University | OTHER |
| The Affiliated Hospital Of Guizhou Medical University | OTHER |
| Longyan City First Hospital | OTHER |
| The Affiliated Hospital of Putian University | OTHER |
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| 1 week |
| D007162 |
| Immunoproteins |
| D001798 | Blood Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D012712 | Serum Globulins |
| D005916 | Globulins |