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Warts are common skin infections caused by human papillomavirus (HPV), which can cause a variety of skin presentations according to its type, site and the immune status .Nongenital warts may be presented as common, plane, plantar, filiform, or mucosal warts .Most people are affected by cutaneous warts, either plantar warts or common warts .prevalence of skin warts is between 3% and 13% and plantar warts are about 30% of skin warts in western world .Majority of cases occur in adolescent and young adults
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group A | Active Comparator | patients will receive intralesional combined digoxin and furosemide , one session every 2 weeks for maximum 6 sessions |
|
| group B | Active Comparator | patients will receive intralesional 5 fluorouracil mixed with 1ml of 2% lignocaine and epinephrine one session every 2 weeks for maximum 6 sessions . |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| combined digoxin and furosemide | Drug | one session every 2 weeks for maximum 6 sessions |
| |
| Measure | Description | Time Frame |
|---|---|---|
| the change in size of plantar wart | measurement the change in size of plantar wart | 3 month |
| the change in number of plantar warts | measurement the change in number of plantar warts | 3 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| samah R Ahmed, resident | Contact | 01128636414 | samah_ragab_post@med.sohag.edu.eg | |
| Essam A Nada | Contact |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag University Hospital | Recruiting | Sohag | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31241843 | Background | Abeck D, Tetsch L, Luftl M, Biedermann T. Extragenital cutaneous warts - clinical presentation, diagnosis and treatment. J Dtsch Dermatol Ges. 2019 Jun;17(6):613-634. doi: 10.1111/ddg.13878. | |
| 21219294 | Background | Kwok CS, Holland R, Gibbs S. Efficacy of topical treatments for cutaneous warts: a meta-analysis and pooled analysis of randomized controlled trials. Br J Dermatol. 2011 Aug;165(2):233-46. doi: 10.1111/j.1365-2133.2011.10218.x. Epub 2011 May 26. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Aug 29, 2024 | |
| Reset | Nov 12, 2024 |
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| 5 fluorouracil |
| Drug |
5 fluorouracil mixed with1ml of 2% lignocaine and epinephrine one session every 2 weeks for maximum 6 sessions . |
|
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Aug 29, 2024 | Nov 12, 2024 |
| ID | Term |
|---|---|
| D005665 | Furosemide |
| D005472 | Fluorouracil |
| ID | Term |
|---|---|
| D013424 | Sulfanilamides |
| D013449 | Sulfonamides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
| D013450 | Sulfones |
| D013457 | Sulfur Compounds |
| D014498 | Uracil |
| D011744 | Pyrimidinones |
| D011743 | Pyrimidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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