The Treatment of Magnesium Sulfate and Nifedipine in Preterm Labor Threat

Comparison of the Effects of Nifedipine and Magnesium Sulfate on Maternal and Fetal Doppler Blood Flow Patterns in Women With Preterm Labor

Comparison of the effects of Nifedipine and MgSO4 therapies on maternal and fetal blood flow.

In this study, the investigators aim to compare the effect of Nifedipine and MgSO4 therapies on Doppler parameters of the uterine, umbilical, middle cerebral arteries, and ductus venous in the first 48 hours of therapy in pregnancies with preterm labor threat and also compare perinatal outcomes after delivery between the groups.

Inclusion Criteria:

• pregnancies with preterm labor threat between 28-34 weeks gestational ages

Exclusion Criteria:

• Cervical dilatation at > 4 cm and/or cervical effacement >80%,
• Multiple pregnancies,
• Pregnancy complications including preeclampsia, ablatio placenta, intrauterine growth restriction, placenta previa, gestational diabetes