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Our study aims to evaluate the role of depression in blood pressure control in ambulatory hypertensive patients.
Research Problem: Hypertension is a multifactorial disease that affects approximately one quarter of the adult population. It is a major risk factor for stroke and cardiovascular disease.
Environmental and psychosocial factors play an important role in hypertension onset and control. The prevalence of depression among hypertensive patients is 26, 8% and its presence is associated with increased risk of cardiovascular-related morbi-mortality. Our study aims to evaluate the role of depression in blood pressure control in ambulatory hypertensive patients. Investigative process: This study is a cross-sectional, multicentric and descriptive study. the investigators intend to include three hundred and two patients. After obtaining their consent, a 24 hour ambulatory blood pressure monitor will be used to evaluate blood pressure control.
Depression was assessed by the 9-item-Patient Health Questionnaire (PHQ-9) in Tunisian dialect. Clinical, socio-environmental, psychosocial and therapeutic and prognosis data will be collected from medical records.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ambulatory patients | Patient with a high blood pressure during regular visit will undertake an ambulatory blood pressure monitoring. Before wearing the device , they will be asked to answer to the questionnaire and the investigators will gather their demographic,clinical characteristics and dietary habits data. Ethical considerations will be undertaken and respected. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blood Pressure Monitoring, Ambulatory | Diagnostic Test | To monitor the blood pressure during 24 hours. |
|
| Measure | Description | Time Frame |
|---|---|---|
| prevalence of depression in uncontrolled hypertensive patients. | The prevalence of depression evaluated by PHQ9 in Tunisian dialect in hypertensive patients with abnormal ambulatory 24 hours blood pressure monitoring | on inclusion |
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Inclusion Criteria:
Non inclusion Criteria :
Exclusion Criteria:
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outpatients consulting in the cardiology department in the different participating centers .
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Aymen NOAMEN, MD | Contact | +21620215773 | no.aymen@gmail.com | |
| Yosra Radaoui, fellow | Contact | +21695651675 | yosra014590@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Aymen NOAMEN, MD | Military Hospital of Tunis | Principal Investigator |
| Wafa Fehri, Pr | Military Hospital of Tunis | Study Chair |
| Lilia Zakhama, Pr |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Interior Security Forces Hospital | Not yet recruiting | La Marsa | Tunis Governorate | Tunisia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26252317 | Result | Li Z, Li Y, Chen L, Chen P, Hu Y. Prevalence of Depression in Patients With Hypertension: A Systematic Review and Meta-Analysis. Medicine (Baltimore). 2015 Aug;94(31):e1317. doi: 10.1097/MD.0000000000001317. | |
| 38545723 | Derived | Raddaoui Y, Ben Amara A, Noamen A, Antit S, Hajri Y, Habli J, Ibn Hadj Amor H, Ben Youssef Y, Zakhama L, Fehri W. Role of depression in blood pressure control. A cross-sectional multicentric study. Tunis Med. 2024 Jan 5;102(1):7-12. doi: 10.62438/tunismed.v102i1.4723. French. |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| D003863 | Depression |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D018660 | Blood Pressure Monitoring, Ambulatory |
| ID | Term |
|---|---|
| D001795 | Blood Pressure Determination |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| interior security forces hospital |
| Study Director |
| Regional hospital of Ben Arous | Recruiting | Ben Arous | Tunisia |
|
| Tahar Sfar regional hospital of Mahdia | Recruiting | Mahdia | Tunisia |
|
| Military Hospital of Tunis | Recruiting | Tunis | 1009 | Tunisia |
|
| D018670 | Monitoring, Ambulatory |
| D008991 | Monitoring, Physiologic |