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The induction dose of rocuronium is typically decided based on the patient's body weight, but the effect duration of rocuronium is variable. Some studies suggest that body composition analysis data, such as skeletal muscle mass or total body water, may correlate better with the duration time of rocuronium. Therefore, we plan to analyse body composition in patients undergoing total intravenous general anesthesia, give the patients a fixed dose (50mg) of rocuronium, and check the correlation between duration time of rocuronium and body composition analysis data.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| rocuronium | The patient will be given 50mg of rocuronium intravenously for induction. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| body composition analysis | Device | Patients will undergo body composition analysis using bioelectical impedance method before anesthesia. |
|
| Measure | Description | Time Frame |
|---|---|---|
| time to TOF1 | correlation between the time from induction to recovery of 1st TOF twitch and age, sex, ASA class, body weight, and body composition analysis data | up to 1 hour after rocuronium administration during induction of anesthesia |
| time to TOF4 | correlation between the time from induction to recovery of 4th TOF twitch and age, sex, ASA class, body weight, and body composition analysis data | up to 1.5 hour after rocuronium administration during induction of anesthesia |
| Measure | Description | Time Frame |
|---|---|---|
| time to loss of TOF | correlation between the time from injection of rocuronium to complete loss of TOF twitch and age, sex, ASA class, body weight, and body composition analysis data | up to 5 minutes after rocuronium administration during induction of anesthesia |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients with ASA class I-II undergoing total intravenous general anesthesia
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samsung Medical Center, Sungkyunkwan University, School of Medicine | Seoul | 06351 | South Korea |
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