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This research is designed to compare proximal gastrectomy anterior anastomosis with pyloroplasty with esophagogastric anastomosis for gastric cancer. Gastroesophageal reflux disease, postoperative quality of life, short term outcomes, and long term outcomes will be compared.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty (GAP) | Experimental | The reconstruction including esophagogastric anastomosis and pyloroplasty for patients who underwent proximal gastrectomy . The anastomosis locate in the anterior of gastric stump. |
|
| Control | Active Comparator | The reconstruction including esophagogastric anastomosis and pyloroplasty for patients who underwent proximal gastrectomy . The anastomosis locate in the posterior or side of gastric stump. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty | Procedure | The location of the anastomosis in the anterior of the gastric stump. Pyloroplasty is added in the procedure |
| Measure | Description | Time Frame |
|---|---|---|
| Gastroesophagus reflux disease apprised by ph monitoring | Ph monitoring by wireless or wire device | 6 months |
| Gastroesophagus reflux disease apprised by questionnaire | PGSAS-45 questionnaire is adopted. | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Surgical complications of proximal gastrectomy for gastric cancer | Surgical complications include anastomotic leakage, anastomotic stricture, postoperative bleeding, pleural effusion, et al. | 1 year |
| Long-term outcome |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yunhong Tian | Recruiting | Nanchong | Sichuan | 637000 | China |
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Total survival time after proximal gastrectomy for gastric cancer
| 5 years |
| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| D005764 | Gastroesophageal Reflux |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |
| D015154 | Esophageal Motility Disorders |
| D003680 | Deglutition Disorders |
| D004935 | Esophageal Diseases |
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