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| Name | Class |
|---|---|
| University of British Columbia | OTHER |
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As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients. Prior studies have found epidural catheters placed via the combined-spinal epidural technique have greater success at surgical conversion for cesarean delivery than catheters placed via traditional techniques. The investigators aim to determine if epidural catheters placed by a DPE technique will also have an increased successful conversion for surgical anesthesia by conducting a retrospective review of all CD during the study period. If an association is found, this could be another benefit of DPE for labor analgesia.
Electronic medical records will be searched for all intrapartum cesarean deliveries performed from February 1, 2017 through May 30, 2021 (Mayo Clinic) and from January 1, 2022 to December 31, 2022 (BC Women's Hospital).
From this list, patients that had cesarean delivery with an epidural catheter will be identified and split into three groups based on the type of neuraxial block listed in the block document of the patient's medical record:
Group 1 - Dural puncture epidural Group 2 - Epidural Group 3 - Combined spinal-epidural
Failure of epidural catheter conversion to surgical anesthesia at cesarean delivery will be defined by requirement of a second anesthetic at the time of surgery, including spinal or repeat epidural techniques or general anesthesia at the time of cesarean delivery
Data Collection: All data will be collected retrospectively from the electronic medical record.
Other data collected from patient electronic records will include:
Maternal demographics: Parity, number of prior cesarean deliveries, weight, height, BMI
Fetal characteristics (birthweight, Apgar scores)
Indication for cesarean delivery
Anesthesiologist (Fellowship trained: Y/N) at time of cesarean delivery
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dural puncture epidural (DPE) | Subjects that received neuraxial labor analgesia of dural puncture epidural for intrapartum cesarean delivery |
| |
| Combined spinal epidural (CSE) | Subjects that received neuraxial labor analgesia of combined spinal epidural for intrapartum cesarean delivery |
| |
| Traditional Epidural | Subjects that received neuraxial labor analgesia of epidural for intrapartum cesarean delivery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Epidural | Procedure | Traditional epidural catheter placement |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Conversion to surgical anesthesia | Number of subject to have success of conversion to surgical anesthesia for intrapartum cesarean delivery | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Parturients that undergo intrapartum cesarean delivery with an epidural already in situ.
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| Name | Affiliation | Role |
|---|---|---|
| Emily Sharpe, MD | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic | Rochester | Minnesota | 55902 | United States | ||
| BC Women's Hospital |
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| Label | URL |
|---|---|
| Mayo Clinic Clinical Trials | View source |
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| ID | Term |
|---|---|
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D007268 | Injections, Epidural |
| D008722 | Methods |
| ID | Term |
|---|---|
| D007278 | Injections, Spinal |
| D007267 | Injections |
| D004333 | Drug Administration Routes |
| D004358 | Drug Therapy |
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| Dural Puncture Epidural (DPE) technique |
| Procedure |
Epidural catheters placed via DPE technique |
|
| Combined Spinal-Epidural (CSE) technique | Procedure | Epidural catheters placed via CSE technique |
|
| Vancouver |
| British Columbia |
| Canada |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D013812 |
| Therapeutics |
| D008919 | Investigative Techniques |