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| Name | Class |
|---|---|
| Kaifeng Central Hospital | OTHER |
| The First Affiliated Hospital of Zhengzhou University | OTHER |
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To investigate the prognostic impacts of the atrial fibrillation burden (AFb) in acute myocardial infarction (AMI) patients who developed paroxysmal new-onset atrial fibrillation (NOAF) during the index AMI hospitalization.
In the present study, investigators retrospectively reviewed the medical records of all acute MI patients who were admitted to the coronary artery unit (CCU) of Shanghai Tenth People's Hospital, KaiFeng Central Hospital, and the First Affiliated Hospital of Zhengzhou University between January 2014 and January 2022. All patients will routinely receive continuous electronic monitoring (CEM) throughout their hospital stay to detect cardiac arrhythmias including the AF events. Of these, patients with AMI without a history of AF who developed a first documented AF episode will be considered for inclusion. The AFb is measured as a percentage (%) by dividing the total AF duration by the total CEM duration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Post-MI NOAF with low AF burden | Patients with post-MI NOAF who had a AF burden<10.87%. The cut-off value of AF burden of 10.87% was identified based on our previous work. |
| |
| Post-MI NOAF with high AF burden | Patients with post-MI NOAF who had a AF burden≥10.87%. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| continuous electronic monitor | Device | All patients with MI hospitalized in the CCU department of Shanghai Tenth People's Hospital, KaiFeng Central Hospital, and the First Affiliated Hospital of Zhengzhou University will receive 24-hour continuous cardiac monitoring until discharge. |
| Measure | Description | Time Frame |
|---|---|---|
| All-cause death | Death from any cause | From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiovascular death | Death from cardiovascular causes | From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years |
| Recurrent myocardial infarction |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with post-MI NOAF
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| Name | Affiliation | Role |
|---|---|---|
| Yidong Wei, M.D., Ph.D. | Shanghai 10th People's Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| KaiFeng Central Hospital | Kaifeng | Henan | China | |||
| The First Affiliated Hospital of Zhengzhou University |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40240944 | Result | Luo J, Qin X, Yuan Y, Zhang Y, Liu J, Wang Y, Zhao G, Xiao L, Zhang X, Fang Y, Shi W, Qin L, Liu B, Wei Y; NOAFCAMI-China Registry Investigators. Association of Atrial Fibrillation Burden With Cardiovascular Outcomes in New-Onset Atrial Fibrillation Complicating Myocardial Infarction. J Am Heart Assoc. 2025 May 20;14(10):e039547. doi: 10.1161/JAHA.124.039547. Epub 2025 Apr 16. | |
| 40974091 |
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| ID | Term |
|---|---|
| D009203 | Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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Rehospitalization for myocardial infarction
| From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years |
| Heart failure hospitalization | HF hospitalization was based on clinical symptoms such as dyspnea and fatigue, and signs of peripheral or pulmonary edema that required hospitalization for intravenous diuretic treatment | From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years |
| Ischemic stroke | Ischemic stroke was identified as the presence of a new focal neurologic deficit thought to be ischemic in origin, with signs or symptoms lasting> 24 hours, and was validated according to radiographic imaging test. | From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years |
| Major bleeding | Bleeding event with a Bleeding Academic Research Consortium (BARC) classification of types 3 or 5. | From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years |
| Zhengzhou |
| Henan |
| China |
| Shanghai Tenth People's Hospital | Shanghai | Shanghai Municipality | 200072 | China |
| Result |
| Luo J, Qin X, Fang Y, Zhang X, Zhang Y, Liu J, Wang Y, Zhao G, Xiao L, Shi W, Qin L, Liu B, Wei Y. Development and external validation of a prognostic model for new-onset atrial fibrillation complicating acute myocardial infarction: insights from the NOAFCAMI-China registry. Eur Heart J Acute Cardiovasc Care. 2026 Mar 10;15(1):32-41. doi: 10.1093/ehjacc/zuaf122. |
| D007238 |
| Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |