Not provided
Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| HNF1608-21 | Other Grant/Funding Number | Northern Norway Regional Health Authoroty |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Nord University | OTHER |
| Helse Nord | INDUSTRY |
Not provided
Not provided
Not provided
Not provided
The current project will fill a knowledge gap in the follow-up of people with Multiple Sclerosis (MS) with mild and moderate disability levels, with the purpose to assess the adequacy of measurement tools for trunk control and balance, functions that are pre-requisites for optimal performance in everyday physical activities.
Trunk control and balance, necessary for daily activities, are frequently impaired in people with MS. Adequate measurement tools for clinical- and research purposes are thus warranted. In this study two measurement tools will be explored:
This study is two-parted, each with a separate aim:
Aim part 1: To determine the validity and reliability of the TIS-modNV across mild and moderate disability levels in the MS population.
Aim part 2: To determine the concurrent validity of the AMTI AccuGait OptimizedTM force plate system compared to the Mini-BESTest across mild and moderate disability levels in the MS population.
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| The modified Trunk Impairment Scale - Norwegian version (TIS-modNV) | TIS-modNV is a six-item ordinal scale measuring impairments of trunk control. The total score ranges between 0-16, where 16 is the best score in trunk control. The scale is developed for and valid and reliable for people with stroke. | 01 January 2023 |
| AMTI AccuGait OptimizedTM (Advanced Mechanical technology, Inc., Watertown, USA) multi-axis force plate system | Force- platform assessing different domains of balance (ie. centre of pressure, sway) in bi- and unipedal standing with eyes open and with eyes closed. | 01 January 2023 |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| The Mini Balance Evaluation Systems Test (Mini-BESTest) | Mini-BESTest is a 14-item ordinal scale, measuring balance in standing and walking. The total scores ranges from 0-28, were 28 is the best score of balance performance. The Norwegian translation of the test is valid and reliable for people with MS. | 01 January 2023 |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
The study will be conducted in Bodø, Nordland county, Norway involving the MS population affiliated to the MS-outpatient clinic at Nordland Hospital (NLSH) and whose adress is in one of the eight municipalities in the Salten region. All people in this population, fitting the inclusion criteria will be requested to participate. People covering the whole range of EDSS 0-6.5 will be recruited. If too many people consents to participate there will be draw.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ellen Christin Arntzen, PHD | Contact | +47 91736886 | ellen.c.arntzen@nord.no | |
| Stine Susanne Haakonsen Dahl, MSc | Contact | +4740473368 | stine.s.dahl@nord.no |
| Name | Affiliation | Role |
|---|---|---|
| Petter Øyen, PHD | Nordlandssykehuset HF | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nordland Hospital Trust | Bodø | 8000 | Norway |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
| Expanded Disability Status Scale (EDSS) |
EDSS is a method of quantifying and monitoring disability in people with MS on a scale from 0-10 and is widely used in clinic and research. A total score of 0 describes "no disability" and a score 10 describes "death due to MS". EDSS scores 0-6.5 (the levels included in this study) encompasses individuals with normal neurological exam/fully ambulatory (score 0) to individuals requiring a walking aids (cane, crutch) to walk about 20m without resting (score 6.5). |
| 01 January 2023 |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |