Full Thickness Resection or Endoscopic Submucosal Dissection for Difficult Colorectal Lesions.

Endoscopic Full Thickness Resection (EFTR) Versus Endoscopic Submucosal Dissection (ESD) in the Treatment of Difficult Colorectal Lesions With Dimensional Cut-off ≤ 30mm: Laterally Spreading Tumor Non Granular Type (LST-NG), "no Lift" Lesions and Residual / Relapses of Previous Resections. Endoscopic.

Compare the efficacy and safety of endoscopic resection a full thickness (EFTR) with Full Thickness Resection Device (FTRD) System versus endoscopic submucosal dissection (ESD) in the treatment of Laterally Spreading Tumor Non Granular Type (LST-NG), "no lift" lesions colon and residual / relapse on scars from previous resections endoscopic colon. The dimensional cut off of these lesions is ≤30mm

Inclusion criteria:

• patients of age >18 years
• Laterally Spreading Tumor Non Granular Type (LST-NG) ≤ 3cm in diameter
• "no-lift" colic injuries ≤ 3cm in diameter
• residual / recurrence on the scar of previous endoscopic resections of the colon ≤ 3cm in diameter

Exclusion criteria:

• pregnant women
• failure to accept or understand the consent to participate in the study
• patients with severe coagulopathies
• patients with short life expectancy (Charlson comorbidity index ≥8)
• patients with expired general clinical conditions (American Society of Anesthesiologists score ≥3)