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| ID | Type | Description | Link |
|---|---|---|---|
| IORG0008839 | Other Identifier | International No: Alexandria University |
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This study will investigate the efficacy of three diode laser wavelengths 445 nm, 660 nm, 970 nm when applied just before placement of composite restoration on reducing postoperative sensitivity from Non-carious cervical lesions (NCCLs) with class V cavity preparation.
In this randomized clinical trial, patients with NCCLs will be included (four teeth in each participant). After class V cavity preparation in the NCCLs, the teeth will be randomly assigned into four groups according to diode laser irradiation wavelength Group 1 (placebo) laser simulation and Group 2 (445 nm) diode laser wavelength, Group 3 (660 nm) diode laser wavelength, and Group 4 (970 nm) diode laser wavelength. Following laser irradiation, the universal self-etch adhesive will be applied and all the cavities will be restored with the same resin composite. Tooth sensitivity to a cold stimulus will be recorded using a visual analogue scale (VAS) before treatment and on follow-up days 1, 14 followed by 1, 3, and 6 month after treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo | Placebo Comparator | Laser Simulation |
|
| 445 nm | Experimental | 445 nm Diode Laser Wavelength (SiroLaser Blue) |
|
| 660 nm | Experimental | 660 nm Diode Laser Wavelength (SiroLaser Blue) |
|
| 970 nm | Experimental | 970 nm Diode Laser Wavelength (SiroLaser Blue) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo | Other | Laser Simulation |
| |
| 445 nm Diode Laser Wavelength |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Dentin Hypersensitivity Assessed from Baseline to After Exposure to Diode Laser Radiation. | Dentin Hypersensitivity is Determined using Cold Stimulus. Utilizing Visual Analog Scale (VAS) Reading 0-10 Where 0 is No Pain, While 10 is the Most Experienced Pain. | Change in Pain Scores From Baseline on the Visual Analog Scale at Day 1, Day 14, Followed by 1,3, and 6 Month Postoperatively. |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical assessment for esthetic, functional, and biological responses to restorative materials. | The restoration's esthetic assessment includes 1. surface luster, 2. surface staining, and 3. color stability and translucency. The functional assessment of the restoration includes 1. fracture and retention, 2. marginal adaptation, 3. wear, and 4. the patient's view . The biological category, ratings include 1. Postoperative sensitivity or hypersensitivity and tooth vitality, 2. Recurrence of carious, erosion, abrasion 3. Tooth integrity (enamel cracks) 4. Periodontal response 5. Adjacent mucosa 6. Oral and general health. Each criterion will be scored 1-5. Each score represents 1. clinically excellent/ very good, 2. clinically good, 3. clinically sufficient/ satisfactory, 4. clinically unsatisfactory, and 5. clinically poor. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Raghda A Hegazy, Bachelor | Pharos University | Principal Investigator |
| El Sayed M Mahmoud, Professor | Alexandria University | Study Chair |
| Ahmed A Holiel, Lecturer | Alexandria University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dentistry | Alexandria | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41831557 | Derived | Holiel AA, Hegazy RA, Sedek EM. Effect of diode laser on dentin surface properties, adhesive performance, and clinical outcomes of non-carious cervical lesion restorations: A 24-month split-mouth randomized controlled trial. J Dent. 2026 May;168:106629. doi: 10.1016/j.jdent.2026.106629. Epub 2026 Mar 12. | |
| 38821658 | Derived |
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In this randomized controlled clinical trial, patients with NCCLs will be included (four teeth in each participant). The teeth will be randomly assigned into four groups according to diode laser irradiation wavelength Group 1 (placebo) laser simulation, Group 2 (445 nm) diode laser wavelength, Group 3 (660 nm) diode laser wavelength, and Group 4 (970 nm) diode laser wavelength.
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The allocation will be hidden from patients, and they will not know which teeth are lased and which will receive the placebo treatment. In addition, for blinding, the restoration procedure is performed by one person, and the cold test is performed by another person who is unaware of the distribution. Furthermore, the statistician will be blinded.
| Radiation |
Irradiated Using a 445 nm Diode Laser Wavelength |
|
| 660 nm Diode Laser Wavelength | Radiation | Irradiated Using a 660 nm Diode Laser Wavelength |
|
| 970 nm Diode Laser Wavelength | Radiation | Irradiated Using a 970 nm Diode Laser Wavelength |
|
| Time frame: Restorations are evaluated for esthetic, functional, and biological properties over follow-up periods of 6 months, 12 months, and 24 months. |
| Hegazy RA, Mahmoud EM, Holiel AA. EFFECT OF LOW-LEVEL DIODE LASER ON DENTIN TOPOGRAPHY AND SYMPTOMATIC NONCARIOUS CERVICAL LESIONS PRIOR TO COMPOSITE RESTORATIONS: A SPLIT-MOUTH RANDOMIZED CONTROLLED TRIAL. J Evid Based Dent Pract. 2024 Jun;24(2):101969. doi: 10.1016/j.jebdp.2024.101969. Epub 2024 Jan 17. |
| ID | Term |
|---|---|
| D003807 | Dentin Sensitivity |
| ID | Term |
|---|---|
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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