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The purpose of this study was to determine the effect of gallstone characteristics for the severity of acute gallstone pancreatitis (GSP)
The timing of cholecystectomy is closely related to the severity of acute gallstone pancreatitis (GSP). The effect of gallstone characteristics (including stone size, number, etc.) for the severity of GSP are currently unknown.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gallstone characteristics | Other | stone size, number, the thickness |
| Measure | Description | Time Frame |
|---|---|---|
| Number of severity of GSP patients | Based on the 2012 Atlanta International Consensus, Mild acute pancreatitis (MAP) is defined as no organ failure and no local or systemic complications. Moderate to severe acute pancreatitis (MSAP) refers to patients with organ failure, local complications, or aggravated complications. Severe acute pancreatitis (SAP) is defined as persistent organ failure for more than 48 hours. | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Modified computed tomography severity index (MCTSI) score | Without knowing the prognosis, two radiologists with eight and ten years of experience independently scored the severity of GSP through the MCTSI score and reached an agreement through discussion when there was disagreement. | 1 month |
| Gallstone size |
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Inclusion Criteria:
Exclusion Criteria:
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Acute gallstone pancreatitis patients
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| Name | Affiliation | Role |
|---|---|---|
| Wenbo Meng, M.D.,Ph.D | LanZhou University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hepatopancreatobiliary Surgery Institute of Gansu Province | Lanzhou | Gansu | 730000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23622135 | Background | Yadav D, Lowenfels AB. The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology. 2013 Jun;144(6):1252-61. doi: 10.1053/j.gastro.2013.01.068. | |
| 32891214 | Background | Boxhoorn L, Voermans RP, Bouwense SA, Bruno MJ, Verdonk RC, Boermeester MA, van Santvoort HC, Besselink MG. Acute pancreatitis. Lancet. 2020 Sep 5;396(10252):726-734. doi: 10.1016/S0140-6736(20)31310-6. |
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If patients permitted
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| ID | Term |
|---|---|
| D010195 | Pancreatitis |
| D042882 | Gallstones |
| ID | Term |
|---|---|
| D010182 | Pancreatic Diseases |
| D004066 | Digestive System Diseases |
| D002769 | Cholelithiasis |
| D001660 | Biliary Tract Diseases |
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The diameter of the stones |
| 1 month |
| Number of stones | The number of gallstones | 1 month |
| 38813815 | Derived | Ma Y, Yue P, Zhang J, Yuan J, Liu Z, Chen Z, Zhang H, Zhang C, Zhang Y, Dong C, Lin Y, Liu Y, Li S, Meng W. Early prediction of acute gallstone pancreatitis severity: a novel machine learning model based on CT features and open access online prediction platform. Ann Med. 2024 Dec;56(1):2357354. doi: 10.1080/07853890.2024.2357354. Epub 2024 May 30. |
| D041761 |
| Cholecystolithiasis |
| D005705 | Gallbladder Diseases |
| D002137 | Calculi |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |