Background: There is scarce literature investigating how patients dispose of unused opioid supplies after their cesarean postoperative pain has faded. The Office of the Surgeon General has identified research on the prevention of opioid use disorder area as well as research on the management of pain as a "Surgeon General Priority" that needs urgent investigation.

Hypothesis: At least 33% of postpartum women discharged home with an opioid prescription and a drug deactivation pouch will use the pouch to dispose of remaining opioids within 30 days of delivery.

Methods: This is a prospective single arm interventional pilot study.

Inclusion criteria:

• Age 18+ at time of enrollment, per ERM
• Delivered ≥26.0 weeks, per ERM
• Status post low transverse cesarean delivery, per ERM
• Physically located on labor & delivery and is postpartum day #1 or #2 at time of enrollment, per ERM
• Opioid prescription has been sent (per ERM) or will be sent (per obstetric team).

Exclusion criteria:

• Positive urine toxicology anytime in pregnancy for non-prescription opioids, fentanyl, amphetamines, benzodiazepines, cannabinoids, LSD, or cocaine, per ERM.

• Buprenorphine or methadone Rx, per ERM

• Patient preferred communication language not English, per ERM

• Documented history, per ERM:

  • Cannabinoid use disorder
  • Hypnotic use disorder
  • Opioid use disorder
  • Stimulant use disorder
  • Fibromyalgia
  • Sickle cell anemia
  • Lumbar disc herniation
  • Multiple sclerosis
  • Trigeminal neuralgia
  • Active cancer
  • Complex regional pain syndrome
  • Systemic lupus erythematosus
  • Rheumatoid arthritis