Effect of Perioperative Gabapentin on Postoperative Opioid Requirements

Effect of Perioperative Gabapentin on Postoperative Opioid Requirements

The purpose of this study is to determine if preoperative gabapentin is noninferior to preoperative and postoperative gabapentin for pain control in patients undergoing surgery for pelvic organ prolapse.

Inclusion Criteria:

• Women > 18 years old
• English-speaking
• Stage > 2 pelvic organ prolapse
• Undergoing pelvic organ prolapse procedure (including native tissue vaginal procedure, native tissue laparoscopic procedure, mesh-augmented laparoscopic procedure, obliterative procedure)
• Planning overnight stay

Exclusion Criteria:

• Renal dysfunction (creatinine clearance <60 mL/min)
• Allergy to acetaminophen and ibuprofen
• Allergy to gabapentin
• Patients on a Controlled Substance Agreement or Opioid Contract from another provider. This information is available in the IU Health electronic medical record, Cerner.