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Normal volunteers were randomly received Sheep ghee or sunflower oil, and before and after the study lipid profile and HS-CRP were measured.
During outpatient clinic visits, potentially eligible individuals were screened for enrollment according to the inclusion and exclusion criteria.
Patients were randomly allocated into the treatment and control groups via the blocked randomization method.
The control group received a normal diet for eight weeks with 10 g of sunflower oil. In the treatment group, sunflower oil was replaced with 10 g of sheep ghee.
50 patients in each group were enrollment. Patients' information, including demographic data and the serum levels of fasting blood sugar (FBS), LDL, HDL, triglyceride (TG), and hs-CRP, were recorded in datasheets twice: once before treatment with sheep ghee and once eight weeks later.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| intervention | Experimental | 10 gr Sheep ghee |
|
| control group | Active Comparator | 10 gr sunflower oil |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sheep ghee | Dietary Supplement | natural sheep ghee, given to patient in a commercial box and intervention group 10 gr per day from sheep ghee |
|
| Measure | Description | Time Frame |
|---|---|---|
| LDL cholesterol | serum LDL level in mg/dl | 2 months |
| total cholesterol | serum total cholesterol in mg/dl | 2 months |
| HDL cholesterol | Serum HDL in mg/dl | 2 months |
| HS-CRP | HS-CRP level in picogram/dl | 2 months |
| Measure | Description | Time Frame |
|---|---|---|
| adverse effect | gastrointestinal, skin, allergy | 2 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Javad Kojuri | Shiraz | Fars | 7134814336 | Iran |
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| ID | Term |
|---|---|
| D008659 | Metabolic Diseases |
| D007249 | Inflammation |
| D050197 | Atherosclerosis |
| D002318 | Cardiovascular Diseases |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001161 | Arteriosclerosis |
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| ID | Term |
|---|---|
| D000074242 | Sunflower Oil |
| ID | Term |
|---|---|
| D010938 | Plant Oils |
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
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clinical trial randomized
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random allocation, open label
| sunflower oil | Dietary Supplement | natural sunflower oil, given to patients in a commercial box and patient use 10 gr of it |
|
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |