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The aim of this study is to investigate the pregnancy, delivery, neonatal, and epilepsy outcomes in individuals with epilepsy undergoing pregnancy at the Maternal and Infant Health Programs at the University Health Network - Sinai Health and followed for epilepsy at the Toronto Western Hospital Epilepsy Clinic. In particular, we are interested in the association between following recommended epilepsy management guidelines for pregnant individuals with epilepsy and those aforementioned outcomes.
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| Measure | Description | Time Frame |
|---|---|---|
| Frequency of adherence to the 2015 Ontario Task Force management of epilepsy in pregnancy | Describe the frequency of adherence to the 2015 Ontario Task Force management of epilepsy in pregnancy (i.e., AED regimen of WWE, frequency of polytherapy, adherence to serum monitoring of lamotrigine, and folic acid supplementation) and its association with year of pregnancy and type of healthcare provider. | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical (neurological, obstetrical, neonatal) outcomes during pregnancy | To determine the association between adherence with the aforementioned guidelines and pregnancy, delivery, neonatal, and neurological outcomes when adjusting for baseline possible confounders. | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Pregnant individuals with epilepsy seen at the Toronto Western Hospital Clinic.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Esther Bui, MD | Contact | 416-603-5320 | Esther.Bui@uhn.ca | |
| Sharon Ng, BA | Contact | 416-603-5320 | Sharon.Ng@uhnresearch.ca |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Health Network | Recruiting | Toronto | Ontario | M5T 2S8 | Canada |
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| ID | Term |
|---|---|
| D004827 | Epilepsy |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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