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| Name | Class |
|---|---|
| University of Santo Tomas Hospital, Philippines | OTHER |
| Baguio General Hospital and Medical Center, Philippines | UNKNOWN |
| East Avenue Medical Center, Philippines | OTHER_GOV |
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This is a pragmatic, multi-center, prospective, observational, non-interventional study and standing database of patients seen at the training institution for cognitive impairment diagnosed with Mild Cognitive Impairment (MCI) or Dementia.
All patients seen at the training institution clinically diagnosed with MCI or dementia by their neurologists will be invited to participate in the study. The investigators will confirm the diagnosis and will explain the study as well as the patient information sheet to the patient and/or legal representative. All eligible patients seen will be assigned a study identification number. Data will be collected by the investigators as the patient undergoes routine clinical evaluation. Corresponding anonymized data on demographics, medical history and risk factors, level of functional impairment, diagnosis, baseline cognitive scores and management will be collected from each patient and entered in the database using a secure online data collection tool.
The investigators will confirm the diagnosis and will explain the study as well as the patient information sheet to the patient and/or legal representative. All eligible patients seen will be assigned a study identification number. Data will be collected by the investigators as the patient undergoes routine clinical evaluation. Corresponding anonymized data on demographics, medical history and risk factors, level of functional impairment, diagnosis, baseline cognitive scores and management will be collected from each patient and entered in the database using a secure online data collection tool. Patients who withdraw participation verbally or in writing are excluded by the investigator from further participation. Withdrawal from the study will be properly documented, including date, time, and reason for withdrawal. Withdrawn subjects will not have their clinical data included in the database.
Collective data will be extracted, summarized, and analyzed every year with oversight provided by the Philippine Neurological Association (PNA). To be able to assess trends and changes over time, data collection for this study will span 3 years from study initiation, after which the utility of an extension or a re-implementation of the study will be assessed by the PNA.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cognitive assessment | Other | The clinical diagnosis will be made based on the criteria set by the investigators. Clinical history and bedside objective assessment in the form of Montreal Cognitive Assessment-Philippines (MoCA-P) or Mini Mental Status Examination-Philippines (MMSE-P), supported by a neuroimaging study (if neuroimaging is not done, diagnosis will be supported by the Hachinski Ischemic Score). |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of dementia and mild cognitive impairment in the study population | To determine the frequency of dementia and mild cognitive impairment in the study | on Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| F frequency of the different types of dementia in the study population | To determine the frequency of the different types of dementia in the study population using the clinical diagnosis | on Day 1 |
| Frequency of risk factors for dementia in the study population |
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Inclusion Criteria
Exclusion Criteria
• Any condition which, in the study investigator's opinion, may jeopardize the patient by his/her participation in this study or affect the validity of the study results.
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Patients seen and evaluated at the participating sites are eligible to be included in the study if they fulfill all inclusion and none of the exclusion criteria.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Rosalina Picar, MD | Contact | (02)87232102 | repicarmd@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Ma. Lourdes C Joson, MD | Philippine Neurological Association | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Baguio General Hospital and Medical Center | Recruiting | Baguio City | Baguio | Philippines |
To be available upon request
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| Jose R. Reyes Memorial Medical Center |
| OTHER_GOV |
| Makati Medical Center | OTHER |
| Quirino Memorial Medical Center, Philippines | UNKNOWN |
| St. Luke's Medical Center, Philippines | OTHER |
| The Medical City, Philippines | OTHER |
| University of the East- Ramon Magsaysay Memorial Medical Center, Philippines | UNKNOWN |
| University of the Philippines Manila - Philippine General Hospital | OTHER |
| Chong Hua Hospital, Philippines | UNKNOWN |
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o determine the frequency of risk factors for dementia in the study population. (age, sex, educational attainment, family history, physical activity, smoking history, alcohol consumption, cardiovascular and cerebrovascular risk factors, chemical exposure, substance abuse, previous psychiatric condition and hearing impairment) |
| on Day 1 |
| Demographic characteristics of patients with dementia or mild cognitive impairment | To describe the demographic characteristics of patients with dementia or mild cognitive impairment as to age at the time of diagnosis, age of onset of symptoms, sex, level of income (of patient or caregiver), location of clinic or hospital, current or previous occupation, educational attainment, neurologic exam findings | on Day 1 |
| Dementia Severity | To categorize dementia severity in each subtype as mild, moderate and severe based on the initial MMSE score at the time of diagnosis. | on Day 1 |
| Diagnostic tests used at the time of the diagnosis | To describe the types of diagnostic tests commonly done at the time of diagnosis, such as neuroimaging, blood tests, EEG | on Day 1 |
| Pharmacologic and nonpharmacologic modalities used | To identify pharmacologic and nonpharmacologic modalities of treatment currently being used in the treatment of dementia | on Day 1 |
| Chong Hua Hospital | Recruiting | Cebu City | Cebu | Philippines |
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| Makati Medical Center | Recruiting | Makati City | National Capital Region | Philippines |
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| The Medical City | Not yet recruiting | Pasig | National Capital Region | Philippines |
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| East Avenue Medical Center | Recruiting | Quezon City | National Capital Region | Philippines |
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| Quirino Memorial Medical Center | Recruiting | Quezon City | National Capital Region | Philippines |
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| St. Luke's Medical Center | Not yet recruiting | Quezon City | National Capital Region | Philippines |
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| Jose R. Reyes Memorial Medical Center | Recruiting | Manila | 1008 | Philippines |
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| University of Santo Tomas Hospiatl | Recruiting | Manila | 1008 | Philippines |
|
| University of the East- Ramon Magsaysay Memorial Medical Center | Recruiting | Manila | Philippines |
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| University of the Philippines - Philippine General Hospital | Not yet recruiting | Manila | Philippines |
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| D003704 | Dementia |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D000073216 | Mental Status and Dementia Tests |
| ID | Term |
|---|---|
| D009483 | Neuropsychological Tests |
| D011581 | Psychological Tests |
| D004191 | Behavioral Disciplines and Activities |
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