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| Name | Class |
|---|---|
| Hannah Dahn | UNKNOWN |
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The hypothesis is that the daily use of brass mesh bolus achieves a comparable dose to every-other-day use of Superflab bolus (current standard of care) in chest wall post-mastectomy patients treated with rotational 6 MV photon delivery.
Intervention: During a standard-of-care 15 fraction radiotherapy treatment, a brass mesh bolus will be used for a single fraction. Small in-vivo dosimeters will be used for three treatment fractions to measure and compare skin doses for quantification purposes.
Comparator: Superflab and no bolus applied as per the treating physician's practice, typically on alternate days. The intervention and comparator tools are to be utilized on each participant.
Primary outcome
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Post-Mastectomy Radiation Therapy Patients | Experimental | Any patient who is going through radiation to their chest wall following mastectomy using a rotational delivery technique and 6 MV, and uses Superflab bolus for some but not all fractions of radiotherapy |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Brass Mesh Bolus | Device | During a standard-of-care 15 fraction radiotherapy treatment, a brass mesh bolus will be used for a single fraction. Small in-vivo dosimeters will be used for three treatment fractions to measure and compare skin doses for quantification purposes. |
| Measure | Description | Time Frame |
|---|---|---|
| Skin Dose Enhancement Under Brass Mesh Bolus | During days one, two, and three of radiation therapy, patients on this study utilize no-bolus, 5-mm thick Superflab bolus, and brass mesh bolus, respectively. Each day, nine in-vivo dosimeters (OSLDs) will be placed on patient skin to sample the skin dose in cGy. As a result, for each patient on this study, skin dose enhancement of brass mesh compared with no-bolus can be related to that of Superflab bolus. At the end of the study, the average and range of skin dose enhancement under brass mesh bolus for a sample size of twenty patients will be reported. | through study completion, an average of 1 year |
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Inclusion Criteria:
Women undergoing rotational chest wall radiotherapy following mastectomy for breast cancer treatment who would utilize Superflab bolus on some, but not all, days of radiotherapy treatment.
Exclusion Criteria:
Patients who require daily bolus due to skin involvement or other high-risk features requiring a high skin dose will not be included.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hannah Dahn, MD | Contact | 902-473-6185 | Hannah.dahn@nshealth.ca |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nova Scotia Health Authority | Recruiting | Halifax | Nova Scotia | B3H 1V7 | Canada |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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This is a single-site study designed to generate data quantifying the skin dose under brass mesh bolus.
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| D017437 |
| Skin and Connective Tissue Diseases |