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| Name | Class |
|---|---|
| St. Anne's University Hospital Brno, Czech Republic | OTHER |
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NUTRITION CCS is a cross-sectional, descriptive study to assess the relationship between body composition and demographic, socioeconomic status, treatment modalities and blood samples of survivors who were in remission. The study was conducted in the Clinic for childhood cancer survivors. The clinic is attended by patients older than 18 years and was built in 2016 at the St. Anne's Hospital in Brno.
NUTRITION CCS is a cross-sectional, descriptive study to assess the relationship between body composition and demographic, socioeconomic status, treatment modalities and blood samples of survivors who were in remission.
Objectives of the study
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| nutritional interventions | Other | Nutritional intervention will be initiated in patients at risk of overweight and obesity. A targeted nutritional intervention will be carried out, which will include consultation on dietary habits and physical activity as determined by diet and physical activity records. Consultations will be aimed at improving lifestyle and maintaining an adequate body weight. |
| Measure | Description | Time Frame |
|---|---|---|
| Define the relationship between the levels of adipokines and cardiometabolic diseases. | Define the relationship between the levels of selected adipokines and the risk of selected chronic diseases, specifically cardiometabolic diseases. | through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Determine the prevalence of hight body fat and decreased skeletal muscle. | Determine the number of patients with a high body fat percentage. In these patients, monitor the responses of selected adipokine levels to targeted nutritional intervention leading to fat mass reduction. | through study completion, an average of 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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The study population is patients who have been treated for childhood or adolescent cancer and who are now being followed up in a dispensary clinic.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tomáš Kepák, MUDr. | Contact | +420724333969 | tomas.kepak@fnusa.cz | |
| Lucie Štrublová, Mgr. | Contact | +420728608476 | luciestrubl@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Julie Bienertová-Vašků, Prof. | Department of Pathological Physiology and RECETOX, Masaryk University, Kamenice 5, | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Masaryk University | Recruiting | Brno | 625 00 | Czechia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38363727 | Derived | Strublova L, Kepak T, Kuruczova D, Zlamal F, Holikova M, Kepakova K, Sterba J, Bienertova-Vasku J. Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study. PLoS One. 2024 Feb 16;19(2):e0298068. doi: 10.1371/journal.pone.0298068. eCollection 2024. |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D009748 | Nutrition Disorders |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D001835 | Body Weight |
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| ID | Term |
|---|---|
| D004035 | Diet Therapy |
| ID | Term |
|---|---|
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
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Patients will undergo analysis of peripheral blood (serum or plasma) or urine including characterization of adipokine profiles/metabolites by targeted or untargeted proteomic approach using mass spectrometry (NanoLC/ESI LTQ-Orbitrap MS/MS) or immunoassays (LUMINEX, ELISA) to identify approximately 15-20 molecules associated with cardiometabolic risk;
| St. Anne Hospital in Brno | Recruiting | Brno | 656 91 | Czechia |
|
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |