TMS-EEG for Cortical Excitability

Electroencephalogram Coupled Non-invasive Brain Stimulation For Assessment of Cortical Excitability

This research study is being done to look at the safety and diagnostic benefit of conducting an TMS(transcranial magnetic stimulation)-EEG measured before and after a brief experimental stimulation session using investigational devices repetitive TMS or transcranial direct current stimulation (tDCS).

Inclusion Criteria - Stroke:

- Acquired brain injury such as ischemic or hemorrhagic stroke or traumatic brain injury.

Inclusion Criteria - Healthy Controls:

- No known active neurological disorder.

Exclusion Criteria - Stroke:

• Pregnancy
• Contraindication to MRI or TMS including metallic implanted objects.
• Medical instability or inability to cooperate during the study as assessed by the treating physician to participate in the study.
• Severe aphasia.
• History of epilepsy.
• History of active depression or treatment resistant depression.
• History of schizophrenia.

Exclusion Criteria - Healthy Controls:

• Pregnancy
• Contraindication to MRI or TMS including metallic implanted objects.
• History of acquired brain injury.