TCA 15% Chemical Peel for Improvement in Hand Lentigines

Use of TCA 15% + 3% Glycolic Acid Chemical Peel for Improvement in Hand Lentigines

This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter. Patients will receive 3 treatments (spaced 4 weeks).

This clinical investigation is a prospective study consisting of a screening visit, 3 treatment visits, and 1 follow-up visit. Baseline and post-treatment photos will be graded and compared.

A total of 20 patients will be recruited. Following informed consent and screening, subjects' dorsal hands will be photographed.

Patients will receive 3 treatments with the 15% TCA + 3% glycolic acid peel every 4-6 weeks on the dorsal hands. Post-treatment, patients will be instructed to apply Aquaphor to the treated area twice daily for 5 days. Patients' hands will be photographed at each visit.

Four to six weeks after their final treatment, subjects will return for photography.

Inclusion Criteria:

• Age >21
• No laser, chemical peel, neuromodulator, filler treatment to the hands in >3 months
• At least 5 lentigines on each hand

Exclusion Criteria:

• Pregnancy
• Breastfeeding
• Allergy to trichloroacetic acid
• Allergy to glycolic acid
• Open wounds on treatment area (hands)
• Active inflammatory disease on treatment area such as atopic dermatitis, psoriasis, dermatomyositis