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| Name | Class |
|---|---|
| Tokyo University | OTHER |
| Nihon University School of Medicine | UNKNOWN |
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The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is still raging across the world and vaccination is expected to lead us out of this pandemic. Although the efficacy of these vaccines is beyond doubt, safety still remains a concern. Liver injury, such as autoimmune hepatitis (AIH), has been reported after COVID-19 vaccination. The aim of this prospective study is to investigate the spectrum and profile of liver injury after COVID-19 vaccination in Asia-Pacific region and to explore the potential risk factors for the development of liver injury.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COVID-19 Vaccination Group | Subjects who have received at lease one dose of approved COVID-19 vaccine |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Approved COVID-19 vaccine | Biological | Vaccination for COVI9-19 |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of subjects with liver injury after COVID-19 vaccination | The COVID-19 vaccine-related liver injury (such as elevated liver enzymes, total bilirubin, etc.) was recorded and its spectrum and profile were evaluated. | Within 24 weeks after COVID-19 vaccination |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects after COVID-19 vaccination
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| Name | Affiliation | Role |
|---|---|---|
| George Lau, MD | Humanity & Health Medical Group | Principal Investigator |
| Masao Omata, MD, PhD | Tokyo University | Principal Investigator |
| Tatsuo Kanda, MD, PhD | Nihon University School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Humanity & Health Medical Group Limited | Hong Kong | Hong Kong | ||||
| Nihon University School of Medicine |
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| Tokyo |
| Japan |
| Tokyo University | Tokyo | Japan |