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| Name | Class |
|---|---|
| Fondation Lopez-Loreta | UNKNOWN |
| Service du sommeil de l'hôpital de l'Hôtel-Dieu | UNKNOWN |
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The proposed research is a non-interventional study made to evaluate different measurements on 1 group of participants, before and after taking a nap, aiming to potentially guide future investigations on nap-modulated tinnitus to better understand this phenomenon.
The main hypothesis is that sleep apneas could be correlated with an increase of tinnitus intensity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nap-modulated participants | Patients with rises of tinnitus intensity after taking a nap or after a short period of sleep. If possible with a characteristic ON/OFF tinnitus (sometimes they have a tinnitus for several days and then stop for several days also). This condition is determined by previous questionnaire. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Napping | Other | Patients are already equipped with electrodes when they pass a test battery before the nap to evaluate mechanisms potentially correlated with tinnitus modulation. Then they do a nap, the nap is stopped when several periods of sleep are seen on EEG (electroencephalogram). Then the test battery is done backwards to evaluate the same measures. |
| Measure | Description | Time Frame |
|---|---|---|
| Average change in minimum masking level of tinnitus (measured in dB) | Minimum masking level is measured with a wideband 20hz-12kHz noise before and after each nap of 5 minutes sleep. | Average from 6 naps of 5 minutes sleep each over 2 days of participation |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between sleep apnea index (number of apnea/hyponea events per hour) and change in minimum masking level of tinnitus (measured in dB) | Sleep apnea index is measured during naps using plethysmography and using air flow measurements through cannulas. | 6 naps of 5 minutes sleep each over 2 days of participation |
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Inclusion Criteria:
Exclusion Criteria:
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Study population is recruited through questionnaires done on different platforms including : SIOPI app, previous potential participants or associations. A lesser part of the study group comes from suggestions of ENTs/Doctors.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Hôtel-Dieu | Paris | 75004 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39644685 | Derived | Guillard R, Philippe V, Hessas A, Faraut B, Michiels S, Park M, Congedo M, Londero A, Leger D. Why does tinnitus vary with naps? A polysomnographic prospective study exploring the somatosensory hypothesis. Hear Res. 2025 Jan;455:109152. doi: 10.1016/j.heares.2024.109152. Epub 2024 Dec 4. |
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| ID | Term |
|---|---|
| D014012 | Tinnitus |
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012891 | Sleep Apnea Syndromes |
| ID | Term |
|---|---|
| D012678 | Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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|
| Correlation between muscular tension (Electromyogram + Trigger Points) and change in minimum masking level of tinnitus (measured in dB) |
Using electromyogram on suprahyoid and masseter muscles, trigger points are done searching for muscle nodes |
| 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation between Middle ear mobility (Impedancemetry) and change in minimum masking level of tinnitus (measured in dB) | Using a multi-frequency impedancemeter | 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation between tubal function (Tubomanometry) and change in minimum masking level of tinnitus (measured in dB) | Using tubomanometer, the eustachian tube is controled (what pressure through the noise is needed) | 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation between articular dysfunction (Physiotherapy Tests) and change in minimum masking level of tinnitus (measured in dB) | Using cervical rotation test + adapted spurling test + jaw mobility in antepulsion and diduction | 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation between change in averaged electroencephalogram alpha band power and change in minimum masking level of tinnitus (measured in dB) | Difference of alpha band power in the EEG signal averaged on the whole scalp between the resting state of 90s before the 5 minutes nap and the one after. | 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation between change in averaged electroencephalogram delta band power and change in minimum masking level of tinnitus (measured in dB) | Difference of delta band power in the EEG signal averaged on the whole scalp between the resting state of 90s before the 5 minutes nap and the one after. | 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation between change in averaged electroencephalogram theta band power and change in minimum masking level of tinnitus (measured in dB) | Difference of theta band power in the EEG signal averaged on the whole scalp between the resting state of 90s before the 5 minutes nap and the one after. | 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation between change in averaged electroencephalogram beta band power and change in minimum masking level of tinnitus (measured in dB) | Difference of beta band power in the EEG signal averaged on the whole scalp between the resting state of 90s before the 5 minutes nap and the one after. | 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation between change in averaged electroencephalogram gamma band power and change in minimum masking level of tinnitus (measured in dB) | Difference of gamma band power in the EEG signal averaged on the whole scalp between the resting state of 90s before the 5 minutes nap and the one after. | 6 naps of 5 minutes sleep each over 2 days of participation |
| Correlation coefficient between audition thresholds (Audiogram) values and change in minimum masking level of tinnitus (measured in dB) | Using an audiometer | 6 naps of 5 minutes sleep each over 2 days of participation |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001049 | Apnea |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |