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The main purpose of this study is to evaluate the risk of postoperative mortality and complications in surgical populations with preoperative renal insufficiency.
This retrospective cohort study use the National Surgical Quality Improvement Program (NSQIP) database to evaluate the risk of postoperative morbidity and mortality in the surgical population. Patients with estimated. glomerular filtration rate(GFR) < 60 ml/min per 1.73 square meter are defined as the renal insufficiency group. Patients with estimated GFR > 90 ml/min per 1.73 square meter are defined as patients without renal insufficiency. Propensity score-matching methods and multivariate logistic regression are used to calculate the risk of postoperative morbidity and mortality.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| renal insufficiency group |
|
| |
| Non-renal insufficiency group | Defined as the study subjects with eGFR > 90 60 ml/min per 1.73 square meter within 90 days before the index surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| estimated GFR calculation | Diagnostic Test | The estimated GFR is computed with Modification of Diet in Renal Disease (MDRD) formula |
|
| Measure | Description | Time Frame |
|---|---|---|
| Risk of postoperative mortality | Calculate risk of postoperative 30-day in-hospital mortality between groups | 30 days after surgery date |
| Measure | Description | Time Frame |
|---|---|---|
| Risk of postoperative morbidities | Postoperative events, including pneumonia, septic shock, stroke, deep vein thrombosis/thrombophlebitis, myocardial infarction and postoperative bleeding are included | 30 days after surgery date |
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Inclusion Criteria:
Exclusion Criteria:
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This study analyze surgical patient data from the American College of SurgeonsNational Surgical Quality Improvement Program (ACS-NSQIP) that was acquired between 2013 and 2018.
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| Name | Affiliation | Role |
|---|---|---|
| Chao-Shun Lin, MD, PhD | Department of Anesthesiology, Taipei Medical University Hospital, 252 Wuxing St., Taipei 110 Taiwan | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Taipei Medical University Hospital | Taipei | Taiwan ( R.o.c.) | 110 | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36974714 | Derived | Liao YC, Chang CC, Chen CY, Liu CC, Liao CC, Shih YV, Lin CS. Preoperative renal insufficiency predicts postoperative adverse outcomes in a mixed surgical population: a retrospective matched cohort study using the NSQIP database. Int J Surg. 2023 Apr 1;109(4):752-759. doi: 10.1097/JS9.0000000000000278. |
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| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |