Investigation of Urinary Biomarkers for the Detection of Prostate Cancer

Investigation of Urinary Biomarkers for the Detection of Prostate Cancer

The aim of this study is to investigate and possibly validate urinary biomarkers for prostate cancer. During this study the focus will be on aberrations of selected genes as prognostic or predictive value has been shown for these genes in tissue, CTC or blood derived cfDNA. Proteins will be explored in urine as well.

This is a prospective study in which urine samples will be collected from healthy volunteers and urine samples and a blood sample from cancer patients with prostate cancer. The participants will be asked to provide a urine sample collected with the ColliPee® device and fill out an online questionnaire to collect usability data. Thereafter, the urine sample will be aliquoted to be used in the study to investigate the different urinary analytes.

Inclusion Criteria:

• Being at least 18 years old
• Being able to understand and read Dutch
• For cancer patients: being diagnosed with prostate cancer
• For healthy volunteers: being male

Exclusion Criteria:

• For cancer patients: suffering from a blood cancer
• For healthy volunteers: diagnosed with cancer