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There are very few randomized controlled trials in open splenectomy surgery, which compare paravertebral block with ESP block. The purpose of this randomized controlled trial is to compare the efficacy of ultrasound-guided paravertebral block with ESP block for perioperative analgesia in open splenectomy .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| general anesthesia+ bilateral US guided erector spinae plane block | Active Comparator | General anesthesia plus ultrasound guided erector spinae plane block with 20 ml bupivacaine 0.2% at T9 |
|
| general anesthesia+ bilateral US guided paravertebral block | Active Comparator | General anesthesia plus bilateral US guided paravertebral block with 7 ml bupivacaine 0.2% at T8 and T10 |
|
| general anesthesia | Active Comparator | general anesthesia plus conventional analgesia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ultrasound guided erector spinae plane block | Procedure | patients will receive combined general anesthesia and ultrasound guided erector spinae plane block with 20 ml of bupivacaine 0.2 % at T9 level bilaterally. |
| Measure | Description | Time Frame |
|---|---|---|
| First time to analgesic requirement | all patients received an IV -PCA system (Accufuser M8P, 60 mL; Woo Young Meditech Co, S.Korea). PCA was prepared with 60 mL of isotonic saline containing 60 mg morphine, and the selected system was adjusted to infuse a 1 mL bolus dose with a lockout interval of 15 minutes while the basal flow rate was switched off. Breakthrough pain was managed with 2mg morphine. | 1st 24 hour |
| Measure | Description | Time Frame |
|---|---|---|
| total analgesic consumption | The total dose of rescue analgesics(morphine) required in 24 hours will be recorded. | 1st 24 hour |
| Numerical rating scale (NRS) | All patients will be monitored in the postoperative period for pain by the NRS score at rest and movement at immediate postoperative (0 min), 30 min, 1, 2, 6,12, and 24 hours. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain Shams University hospitals | Cairo | Egypt |
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| ultrasound guided paravertebral block | Procedure | patients will receive combined general anesthesia and ultrasound guided paravertebral block with 7 ml of bupivacaine 0.2 % at T8 and T10 bilaterally. |
|
| conventional analgesia | Drug | patients will receive combined general anesthesia and conventional analgesia |
|
| 1st 24 hour |
| ID | Term |
|---|---|
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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