Evaluation of D-chiro-inositol Treatments

Evaluation of the Effects of D-chiro-inositol in Female Healthy Volunteer

Healthy women will take tablets containing 600 mg D-chiro-inositol twice per day for one month. We will evaluate metabolic and hormonal.parameters, as insulienmia, glycemia, estradiol, testosterone.

Inclusion Criteria:

• Good state of health;
• Regular menstrual cycle.

Exclusion Criteria:

• pregnancy;
• delivery in the previous 6 months;
• currently breastfeeding;
• menopause;
• alcohol or drug abuse;
• insulin resistance defined as HOMA-IR index greater than or equal to 2.5;
• other medical morbidities, such as hypertension, PCOS, or diabetes;
• oligomenorrhea or amenorrhea;
• current treatment with corticosteroids or hormones (oral contraceptives, estrogensic, progestogensin);
• use of GnRH analogues, SERMs, or SPRMs within the previous 6 months.