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| Name | Class |
|---|---|
| Brain Hospital of Hunan Provincial | UNKNOWN |
| The First Affiliated Hospital of Zhengzhou University | OTHER |
| The Affiliated Hospital of Xuzhou Medical University | OTHER |
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This study will investigate the epidemiology, risk factors, diagnostics, treatment, and the long-term prognosis of cerebral venous thrombosis in China.
The epidemiology, risk factors, diagnosis and treatment of Cerebral Venous Thrombosis (CVT) in China are still unclear. A retrospective hospital-based study will be conducted at fifty different hospitals across 31 provinces in China. This study will use ICD-10 to search patients diagnosed with CVT between January 1, 2018 and June 15, 2022 across 31 provinces and municipalities of 104 hospitals in China. Risk factors, clinical and radiological findings, treatment and short-term outcomes will be recorded from the hospital record system. Finally, a prospective follow-up will be conducted for all of the patients enrolled above. By combining data collected from retrospective hospital records with the new follow-up, it will be possible to better understand the epidemiology, risk factors, diagnosis, treatment and the long-term prognosis of CVT in China.
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| Measure | Description | Time Frame |
|---|---|---|
| Favorable clinical outcome (modified Rankin score 0-1) | Baseline to three years | |
| All-cause mortality | A combination of death form of all causes | Baseline to three years |
| Measure | Description | Time Frame |
|---|---|---|
| Recurrence of cerebral venous thrombosis | Diagnosed by DSA, MRV, CTV or HR-MRI | Baseline to three years |
| Favorable clinical outcome (modified Rankin score 0-2) | Baseline to three years |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with cerebral venous sinus thrombosis, deep cerebral vein thrombosis and cortical vein thrombosis.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xuan Wu Hospital,Capital Medical University | Beijing | Beijing Municipality | 100069 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38622893 | Derived | Bian H, Wang X, Liu L, Yan F, Lu S, Hui W, Zhou C, Duan J, Li M, Chen J, Meng R, Cao L, Wang L, Ji X. Multicenter registry study of cerebral venous thrombosis in china (RETAIN-CH): Rationale and design. Brain Behav. 2024 Apr;14(4):e3353. doi: 10.1002/brb3.3353. |
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| ID | Term |
|---|---|
| D020767 | Intracranial Thrombosis |
| ID | Term |
|---|---|
| D002542 | Intracranial Embolism and Thrombosis |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| Guizhou Provincial People's Hospital |
| OTHER |
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| Headache after CVT | Headache Impact Test - 6 score | Baseline to three years |
| Incidence of hemorrhagic complication | Extracranial hemorrhage (fall in hemoglobin of 2 gram/dl or more within 48 hours) or intracranial hemorrhage | Baseline to three years |
| Recanalization rate of cerebral venous system | Baseline to three years |
| Incidence of epilepsy | Baseline to three years |
| Incidence of acute ischemic stroke | Baseline to three years |
| Incidence of pulmonary embolism | Baseline to three years |
| Psychological distress after CVT | Population Health Questionnaire (PHQ)-9 score | Baseline to three years |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D013923 | Thromboembolism |
| D016769 | Embolism and Thrombosis |