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The regional methods of anesthesia for the neurosurgical operations of the spine and spinal cord reducing the needs for opioids intra operatively and reducing pain in the postoperative period, decrease the numbers of failed back syndrome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| General anesthesia | Experimental | induction: propofol 1.5-2.5 mg\kg IV bolus and fentanyl 1-2 mcg\kg maintenance anesthesia: sevoflurane, doses of the inhalation agent according to bispectral index (BIS) monitor ( target BIS level 40-60) and fentanyl 1-5 mcg\kg\h. |
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| Combined anesthesia: general anesthesia and Erector spinae plane block (ESP block) | Experimental | induction: propofol 1.5-2.5 mg\kg IV bolus and fentanyl 1-2 mcg\kg ESP- block with US control with single shot of local anesthetic ( bupivacaine 0.375% or 0.25% 20-30 ml) is performed after induction. maintenance anesthesia: sevoflurane, doses of the inhalation agent according to BIS monitor ( target BIS level 40-60) and fentanyl 0.5-1.5 mcg\kg\h. |
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| Combined anesthesia: General anesthesia and Thoraco-lumbar interfacial plane block (TLIP block) | Experimental | induction: propofol 1.5-2.5 mg\kg IV bolus and fentanyl 1-2 mcg\kg TLIP- block with US control with single shot of local anesthetic ( bupivacaine 0.25% 15 ml or mixed bupivacaine 0.25% 7.5 ml and lidocaine 2% 7.5 ml) is performed after induction. maintenance anesthesia: sevoflurane, doses of the inhalation agent according to BIS monitor ( target BIS level 40-60) and fentanyl 0.5-1.5 mcg\kg\h. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| regional anesthesia | Procedure | regional anesthesia in lumbar surgery, TLIP block in spinal surgery, ESP block in spinal surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| A Visual Analogue Scale (numerical rating scale (NRS) | minimum 0 ( no pain), maximum 10 (the worst pain ever) | 2 hours after surgery |
| A Visual Analogue Scale (numerical rating scale (NRS) | minimum 0 ( no pain), maximum 10 (the worst pain ever) | 6 hours after surgery |
| A Visual Analogue Scale (numerical rating scale (NRS) | minimum 0 ( no pain), maximum 10 (the worst pain ever) | 24 hour after surgery |
| A Visual Analogue Scale (numerical rating scale (NRS) | minimum 0 ( no pain), maximum 10 (the worst pain ever) | 48 hour after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| A Visual Analogue Scale (numerical rating scale (NRS) | minimum 0 ( no pain), maximum 10 (the worst pain ever) | 1 month after surgery |
| A Visual Analogue Scale (numerical rating scale (NRS) | minimum 0 ( no pain), maximum 10 (the worst pain ever) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yelyzaveta Plechysta, MD | Contact | +380636494490 | plechysta.y@dobrobut.ua |
| Name | Affiliation | Role |
|---|---|---|
| Yelyzaveta Plechystaya, MD | chief of the anesthesia department | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anesthesia department Medical Network Dobrobut | Recruiting | Kyiv | 01000 | Ukraine |
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| 3 month after surgery |
| ID | Term |
|---|---|
| D007405 | Intervertebral Disc Displacement |
| D013130 | Spinal Stenosis |
| D055111 | Failed Back Surgery Syndrome |
| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D006547 | Hernia |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D001416 | Back Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D000765 | Anesthesia, Conduction |
| ID | Term |
|---|---|
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
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