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The aim of this current study is to estimate serum level of YKL-40, serum total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tadalafil group | Active Comparator | Each patient will be treated by tadalafil 5mg daily for 3months |
|
| control group | No Intervention | Estimation of serum YKL-40, platelet indices and serum total testosterone in healthy individuals in camparing with tadalafil group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tadalafil 5mg | Drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Serum YKL-40 and platelets indices in erectile dysfunction | Measurement of YKL-40 and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil. | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Effect of tadalafil on Erectile dysfucntion patients | To show the therapeutic effect of tadalafil in dose 5 mg daily on Erectile dysfucntion patients and assess their response by international index of erectile function (IIEF-5) | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aswan university | Aswān | 81528 | Egypt |
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| ID | Term |
|---|---|
| D007172 | Erectile Dysfunction |
| ID | Term |
|---|---|
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D012735 | Sexual Dysfunction, Physiological |
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| ID | Term |
|---|---|
| D000068581 | Tadalafil |
| ID | Term |
|---|---|
| D002243 | Carbolines |
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| D052801 | Male Urogenital Diseases |
| D020018 | Sexual Dysfunctions, Psychological |
| D001523 | Mental Disorders |
| D026121 |
| Indole Alkaloids |
| D007211 | Indoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006575 | Heterocyclic Compounds, 3-Ring |