| Primary | Young Mania Rating Scale (YMRS) | Measuring total Mania scores; 11 items used to access severity of mania (total score 0-60); higher scores represent higher severity of symptoms | | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
| | | Title | Denominators | Categories |
|---|
| Baseline | | | Title | Measurements |
|---|
| - OG0005.5(0.5 to 6)
- OG00111.8(9.575 to 13.25)
- OG0027.5(5.5 to 8)
|
| | Day 5 |
| |
| Primary | Young Mania Rating Scale (YMRS) | Measuring total Mania scores; 11 items used to access severity of mania (total score 0-60); higher scores represent higher severity of symptoms | 'Mice" R package used for 1 individual 1 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Primary | Young Mania Rating Scale (YMRS) | Measuring total Mania scores; 11 items used to access severity of mania (total score 0-60); higher scores represent higher severity of symptoms | 'Mice' R package used to impute 5 individuals 3 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Primary | Altman Self-Rating Mania Scale (ASRM) | The ASRM is a 5-item self rating mania scale, assessing the presence and severity of manic symptoms. The scores for all five items are added together, resulting in a total score that can range from 0 to 20. A score of 6 or higher indicates a high probability of a manic or hypomanic condition. | | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Primary | Altman Self-Rating Mania Scale (ASRM) | The ASRM is a 5-item self rating mania scale, assessing the presence and severity of manic symptoms. The scores for all five items are added together, resulting in a total score that can range from 0 to 20. A score of 6 or higher indicates a high probability of a manic or hypomanic condition. | 'Mice' R package used to impute 1 individual's 1 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Primary | Altman Self-Rating Mania Scale (ASRM) | The ASRM is a 5-item self rating mania scale, assessing the presence and severity of manic symptoms. The scores for all five items are added together, resulting in a total score that can range from 0 to 20. A score of 6 or higher indicates a high probability of a manic or hypomanic condition. | 'Mice' R package used to impute 5 individuals 3 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Primary | Psychiatric Hospitalizations for Mania Post Study Entry | Psychiatric hospitalization for mania. Count of hospitalizations from baseline to end of study period assessed at Day 5, 1 Month & 3 Month. | Cumulative count of hospitalizations for mania from baseline to end of study | Posted | | Number | | number of hospitalizations | | Cumulative count of hospitalizations for mania from baseline to end of study | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Secondary | Balloon Analogue Risk Task (BART) | The BART is a computerized task the measures risk-taking behavior. Participants are tasked with inflating the virtual balloon. The number of pumps a participant chooses to make on each balloon is used as a measure of their risk-taking behavior. More pumps generally indicate a higher tolerance for risk. The balloon bursts at a given point if the participant overfills it. Number of popped balloons reported for a given trial. | | Posted | | Median | Inter-Quartile Range | popped balloons | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Secondary | Balloon Analogue Risk Task (BART) | The BART is a computerized task the measures risk-taking behavior. Participants are tasked with inflating the virtual balloon. The number of pumps a participant chooses to make on each balloon is used as a measure of their risk-taking behavior. More pumps generally indicate a higher tolerance for risk. The balloon bursts at a given point if the participant overfills it. Number of popped balloons reported for a given trial. | 'Mice' R package used to impute 1 individual's 1 Month data | Posted | | Median | Inter-Quartile Range | popped balloons | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | |
|
| Secondary | Balloon Analogue Risk Task (BART) | The BART is a computerized task the measures risk-taking behavior. Participants are tasked with inflating the virtual balloon. The number of pumps a participant chooses to make on each balloon is used as a measure of their risk-taking behavior. More pumps generally indicate a higher tolerance for risk. The balloon bursts at a given point if the participant overfills it. Number of popped balloons reported for a given trial. | 'Mice' R packaged used to impute 5 individuals' 3 Month data | Posted | | Median | Inter-Quartile Range | popped balloons | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | |
|
| Secondary | The Go/No Go Task | The Go/No Go Task is a computerized task that measures impulsiveness. Participants presented with Go (to respond) and no Go (when not to respond) instructions. Two trials are performed. The first trial consist of two distinct auditory stimuli (both Go stimuli) where the participant is asked to respond with a different number of mouse clicks to the stimuli respectively. The second trial, has a no Go stimuli (where the participant is suppose to withhold a response) and a go stimuli. Reaction time for correct trials only for the entire task are reported in milliseconds. | | Posted | | Median | Inter-Quartile Range | reaction time (ms) on task | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | |
|
| Secondary | The Go/No Go Task | The Go/No Go Task is a computerized task that measures impulsiveness. Participants presented with Go (to respond) and no Go (when not to respond) instructions. Two trials are performed. The first trial consist of two distinct auditory stimuli (both Go stimuli) where the participant is asked to respond with a different number of mouse clicks to the stimuli respectively. The second trial, has a no Go stimuli (where the participant is suppose to withhold a response) and a go stimuli. Reaction time for correct trials only for the entire task are reported in milliseconds. | 'Mice' R package used for 1 individual's 1 Month data | Posted | | Median | Inter-Quartile Range | reaction time (ms) on task | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 |
|
| Secondary | The Go/No Go Task | The Go/No Go Task is a computerized task that measures impulsiveness. Participants presented with Go (to respond) and no Go (when not to respond) instructions. Two trials are performed. The first trial consist of two distinct auditory stimuli (both Go stimuli) where the participant is asked to respond with a different number of mouse clicks to the stimuli respectively. The second trial, has a no Go stimuli (where the participant is suppose to withhold a response) and a go stimuli. Reaction time for correct trials only for the entire task are reported in milliseconds. | 'Mice' R package used to impute 5 individuals 3 Month data | Posted | | Median | Inter-Quartile Range | reaction time (ms) on task | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 |
|
| Secondary | Electroencephalography (EEG) Resting State | Measuring neural activity at rest consisting of 5 minutes of eyes-open resting-state EEG (rsEEG) was recorded. Fast Fourier transformations were conducted on data, resulting in 4 frequency bands: delta/theta, alpha, beta, and gamma. | Delta/Theta represents the range of 2-7Hz | Posted | | Median | Inter-Quartile Range | peak amplitude measured in microvolts | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Secondary | Electroencephalography (EEG) Resting State | Measuring neural activity at rest consisting of 5 minutes of eyes-open resting-state EEG (rsEEG) was recorded. Fast Fourier transformations were conducted on data, resulting in 4 frequency bands: delta/theta, alpha, beta, and gamma. | 'Mice' R package used to impute 1 individual's 1 Month Data. Delta/Theta represents the range of 2-7Hz. | Posted | | Median | Inter-Quartile Range | peak amplitude measured in microvolts | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Secondary | Electroencephalography (EEG) Resting State | Measuring neural activity at rest consisting of 5 minutes of eyes-open resting-state EEG (rsEEG) was recorded. Fast Fourier transformations were conducted on data, resulting in 4 frequency bands: delta/theta, alpha, beta, and gamma. | 'Mice' R package used to impute 5 individuals 3 Month data. Delta/Theta represents the range of 2-7Hz. | Posted | | Median | Inter-Quartile Range | peak amplitude measured in microvolts | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Secondary | Reinforcement Learning Task | The reinforcement learning task is a monetary based learning tasks that included reward and punishment trails. The task presents multiple trials of stimuli where the participant chooses 1 of 2 stimuli presented at a time (one of which is associated with punishment represented by loss of monetary reward while the other is associated with gain of monetary reward). EEG is record during the task and signal is captured during the participants choose and the feedback received. Reported is the peak beta/gamma range response derived from the EEG during reward feedback. This measurement is used from the baseline assessment to inform the personalized beta-gamma range stimulation for the Personalized Beta-Gamma tACS group. | | Posted | | Median | Inter-Quartile Range | peak frequency measured in hertz | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | |
|
| Secondary | Reinforcement Learning Task | The reinforcement learning task is a monetary based learning tasks that included reward and punishment trails. The task presents multiple trials of stimuli where the participant chooses 1 of 2 stimuli presented at a time (one of which is associated with punishment represented by loss of monetary reward while the other is associated with gain of monetary reward). EEG is record during the task and signal is captured during the participants choose and the feedback received. Reported is the peak beta/gamma range response derived from the EEG during reward feedback. This measurement is used from the baseline assessment to inform the personalized beta-gamma range stimulation for the Personalized Beta-Gamma tACS group. | 'Mice' R package used to impute 1 individual's 1 Month data | Posted | | Median | Inter-Quartile Range | peak frequency measured in hertz | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. |
|
| Secondary | Reinforcement Learning Task | The reinforcement learning task is a monetary based learning tasks that included reward and punishment trails. The task presents multiple trials of stimuli where the participant chooses 1 of 2 stimuli presented at a time (one of which is associated with punishment represented by loss of monetary reward while the other is associated with gain of monetary reward). EEG is record during the task and signal is captured during the participants choose and the feedback received. Reported is the peak beta/gamma range response derived from the EEG during reward feedback. This measurement is used from the baseline assessment to inform the personalized beta-gamma range stimulation for the Personalized Beta-Gamma tACS group. | 'Mice' R package used for imputing 5 individuals 3 Month data | Posted | | Median | Inter-Quartile Range | peak frequency measured in hertz | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. |
|
| Secondary | Social Functioning Scale (SFS) | The SFS a self-report questionnaire initially designed for people diagnosed with Schizophrenia; consists of 79 items designed to reflect the social skills and performances in different areas of life. Subscores are summed together for a total score. Total score of SFS ranges between 0-223 points. Higher scores mean better social functioning. | | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Secondary | Social Functioning Scale (SFS) | The SFS a self-report questionnaire initially designed for people diagnosed with Schizophrenia; consists of 79 items designed to reflect the social skills and performances in different areas of life. Subscores are summed together for a total score. Total score of SFS ranges between 0-223 points. Higher scores mean better social functioning. | 'Mice' R package used to impute 1 individual's 1 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Secondary | Social Functioning Scale (SFS) | The SFS a self-report questionnaire initially designed for people diagnosed with Schizophrenia; consists of 79 items designed to reflect the social skills and performances in different areas of life. Subscores are summed together for a total score. Total score of SFS ranges between 0-223 points. Higher scores mean better social functioning. | 'Mice' R package used to impute 5 individuals 3 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
|
| Secondary | Global Assessment of Functioning (GAF) | The GAF measures how symptoms affect individuals day-to-day life; scored from 0 to 100 | | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
| |
| Secondary | Global Assessment of Functioning (GAF) | The GAF measures how symptoms affect individuals day-to-day life; scored from 0 to 100 | 'Mice' R package used to impute 1 individual's 1 Month data | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Global Assessment of Functioning (GAF) | The GAF measures how symptoms affect individuals day-to-day life; scored from 0 to 100 | 'Mice' R package used to impute 5 individuals 3 Month data | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Positive and Negative Syndrome Scale (PANSS) | 30 items included in the PANSS measuring positive, negative and general symptoms; 7 related to positive symptoms, 7 for negative symptoms, and 16 for general psychopathology Scale. Ranges are 7 to 49 for the Positive and Negative Scales, and 16 to 112 for the General Psychopathology Scale. Scores summed for Total Score on scale (30 to 210). Higher scores mean worse clinical symptoms. Total score reported. | | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Positive and Negative Syndrome Scale (PANSS) | 30 items included in the PANSS measuring positive, negative and general symptoms; 7 related to positive symptoms, 7 for negative symptoms, and 16 for general psychopathology Scale. Ranges are 7 to 49 for the Positive and Negative Scales, and 16 to 112 for the General Psychopathology Scale. Scores summed for Total Score on scale (30 to 210). Higher scores mean worse clinical symptoms. Total score reported. | 'Mice' R package used to impute 1 individuals 1 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | |
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| Secondary | Positive and Negative Syndrome Scale (PANSS) | 30 items included in the PANSS measuring positive, negative and general symptoms; 7 related to positive symptoms, 7 for negative symptoms, and 16 for general psychopathology Scale. Ranges are 7 to 49 for the Positive and Negative Scales, and 16 to 112 for the General Psychopathology Scale. Scores summed for Total Score on scale (30 to 210). Higher scores mean worse clinical symptoms. Total score reported. | 'Mice' R package used to impute 5 individuals 3 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | |
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| Secondary | Montgomery-Åsberg Depression Rating Scale (MADRS) | The MADRS is designed to measure depression and severity of symptoms; 0 to 6 indicates no depression, 7 to 19 indicates mild depression, 20 to 34 indicates moderate depression, 35 and greater indicates severe depression. Total score reported (0 to 60). | | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Montgomery-Åsberg Depression Rating Scale (MADRS) | The MADRS is designed to measure depression and severity of symptoms; 0 to 6 indicates no depression, 7 to 19 indicates mild depression, 20 to 34 indicates moderate depression, 35 and greater indicates severe depression. Total score reported (0 to 60). | 'Mice' R package used to impute 1 individual's 1 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Montgomery-Åsberg Depression Rating Scale (MADRS) | The MADRS is designed to measure depression and severity of symptoms; 0 to 6 indicates no depression, 7 to 19 indicates mild depression, 20 to 34 indicates moderate depression, 35 and greater indicates severe depression. Total score reported (0 to 60). | 'Mice' R package used to impute 5 individuals 3 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Barratt Impulsiveness Scale-11 (BIS-11) | The BIS-11 is designed to assess the personality/behavioral impulsiveness. The BIS-11 has 30 items and is scored appropriately. Scored to yield a total score, three second-order factors, and six first-order factors. Each question has a 4-point scale ranging from 1 (rarely/never) to 4 (almost always/always). Higher scores mean more impulsive behavior. Total score reported (30-120). | | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Barratt Impulsiveness Scale-11 (BIS-11) | The BIS-11 is designed to assess the personality/behavioral impulsiveness. The BIS-11 has 30 items and is scored appropriately. Scored to yield a total score, three second-order factors, and six first-order factors. Each question has a 4-point scale ranging from 1 (rarely/never) to 4 (almost always/always). Higher scores mean more impulsive behavior. Total score reported (30-120). | 'Mice' R package used to impute 1 individual's 1 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | |
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| Secondary | Barratt Impulsiveness Scale-11 (BIS-11) | The BIS-11 is designed to assess the personality/behavioral impulsiveness. The BIS-11 has 30 items and is scored appropriately. Scored to yield a total score, three second-order factors, and six first-order factors. Each question has a 4-point scale ranging from 1 (rarely/never) to 4 (almost always/always). Higher scores mean more impulsive behavior. Total score reported (30-120). | 'Mice' R package used to impute 5 individuals 3 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a scale | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | |
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| Secondary | Brief Assessment of Cognition (BACS) | The BACS is designed to assess several domains of cognition; Verbal Memory; Processing Speed; Working Memory; Verbal Fluency; Motor Function; Executive Functioning. Higher scores indicate better cognitive functioning. Total score reported after being transformed into z score based on normative scoring provide by test makers. | | Posted | | Median | Inter-Quartile Range | score on a test | | Change from baseline to 5 Day follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Brief Assessment of Cognition (BACS) | The BACS is designed to assess several domains of cognition; Verbal Memory; Processing Speed; Working Memory; Verbal Fluency; Motor Function; Executive Functioning. Higher scores indicate better cognitive functioning. Total score reported after being transformed into z score based on normative scoring provide by test makers. | 'Mice' R package used to impute 1 individual's 1 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a test | | Change from baseline to 1-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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| Secondary | Brief Assessment of Cognition (BACS) | The BACS is designed to assess several domains of cognition; Verbal Memory; Processing Speed; Working Memory; Verbal Fluency; Motor Function; Executive Functioning. Higher scores indicate better cognitive functioning. Total score reported after being transformed into z score based on normative scoring provide by test makers. | 'Mice' R package used to impute 5 individuals 3 Month data. Total score reported. | Posted | | Median | Inter-Quartile Range | score on a test | | Change from baseline to 3-month follow-up | | | | ID | Title | Description |
|---|
| OG000 | HD-tDCS | HD-tDCS; Two, twenty-minute sessions of tDCS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Electrical-Current Stimulation: Non-frequency dependent transcranial electrical stimulation condition for 5 days of twice a day treatment | | OG001 | HD-tACS (Alpha, 10 Hz) | 10 Hz HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Transcranial Alternate-Current Stimulation: 10hz HD-tACS stimulation condition will target alpha (10 Hz) for 5 days of twice a day treatment. | | OG002 | Personalized Beta-Gamma tACS | Personalized HD-tACS; Two, twenty-minute sessions of tACS to the OFC for 5 days (10 total sessions). High-Definition Personalized Transcranial (Beta-Gamma) Electrical Stimulation: Personalized beta-gamma electrical stimulation for 5 days of twice a day treatment |
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