This is a prospective, multicenter, non-interventional study. Findings are analyzed using epidemiological methods.

This NIS shall document the therapy of chronic iron overload in a broad patient population with either of the approved iron chelators in Germany. The choice of patients and the therapy according to the SmPC follows the clinical routine exclusively. The regular observation time per patient is 24 months.

Corresponding to the clinical routine, follow up visits can be documented after approximately 1, 3, 6, 9, 12 and 18 month with a close out visit after 24 month. In case the iron chelator is switched, the visit scheme should be passed through once again.

Inclusion Criteria:

Male and female adult patients suffering from chronic iron overload

• who never received an iron chelator directly before starting an iron chelation therapy
• who received an iron chelation therapy for less than 6 month
• who interrupted an iron chelation therapy for longer than 6 months and will receive an iron chelation therapy again
• who signed the informed consent

Exclusion Criteria:

-

Male and female adult patients suffering from chronic iron overload receiving an iron chelation therapy