Study of Microbiological Diversity in Exhaled Air in COPD and Free of COPD

Study of Microbiological Diversity in Exhaled Air in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD) and Subjects Free of COPD

COPD and non-COPD patients will be included in the study after collection of their non-objection. The exhalation will be collected to study the microbiological diversity of human exhalations.

a second collection for the year +1 will be made, at the same time (between October and March).

The subjects will be recruited during a medical visit in the Departments of Pneumology and Occupational and Environmental Pathologies.

After information and inclusion of the subject in the study, a collection of clinical data, the state of health and the smoking status of the subject will be carried out by the clinical study technician.

A collection of the exhalation will also be carried out by the clinical study technician.

Several groups of subjects will be formed according to pathologies (COPD versus non-COPD), age and smoking status

Inclusion Criteria:

For COPD:

• Patients with chronic obstructive pulmonary disease
• Age: over 18

For non-COPD

• Absence of chronic obstructive pulmonary disease
• Age: between 18 and 30 years old and between 45 and 70 years old

Exclusion Criteria:

• Taking certain medications in the month preceding the sample (antibiotics, systemic corticosteroids, immunosuppressants)
• Person under guardianship or curatorship
• Pregnant or breastfeeding women
• Person unable to express his/her opposition, person deprived of liberty
• Existence of a chronic infectious pulmonary pathology such as (dilation of the bronchi, cystic fibrosis)