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Preterm infants (gestational age (GA) at birth < 31 weeks) admitted to the University of Minnesota Masonic Children's Hospital NICU will have a Dexcom G6 sensor Continuous Glucose Monitor (CGM) placed shortly after consent and wear the device for up to 10 days. The low alarm threshold will be set at 60 mg/dL or 80mg/dL (depending on whether they are receiving continuous insulin) to detect the potential for hypoglycemia. A suggestion will be made to the clinical team to draw a blood glucose to correlate with CGM values ≤60 mg/dL and the infant will be treated according to Neonatal Intensive Care Unit (NICU) protocol for corroborating blood glucose levels. Infants will also be monitored per current NICU protocol (blood glucose checks every 1-2 hours while on insulin) and treated accordingly. Clinical data and long-term growth, body composition and neurodevelopmental outcomes will be recorded.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dexcom G6 sensor Continuous Glucose Monitor (CGM) | All participants will be assigned to use the continuous glucose monitor |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexcom G6 sensor Continuous Glucose Monitor (CGM) | Device | The device used as part of the study is to obtain results for glucose testing for research only and not for diagnostic purposes. |
| Measure | Description | Time Frame |
|---|---|---|
| Detection of hypo- and hyperglycemia - CGM device | Proportion of CGM device readings that match blood glucose readings | 10 days post placement of CGM |
| Detection of hypo- and hyperglycemia - 60 mg/dL | % time below 60 mg/dL | 10 days post placement of CGM |
| Detection of hypo- and hyperglycemia - 180 mg/dL | % time above 180 mg/dL | 10 days post placement of CGM |
| Detection of hypo- and hyperglycemia - AEs | % of infants with adverse events secondary to CGM placement or wear | 10 days post placement of CGM |
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Inclusion Criteria:
Exclusion Criteria:
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Preterm infants (gestational age (GA) at birth <31 weeks) admitted to the University of Minnesota Masonic Children's Hospital
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota | Minneapolis | Minnesota | 55455 | United States |
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| ID | Term |
|---|---|
| D006943 | Hyperglycemia |
| D007003 | Hypoglycemia |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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