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The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.
The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.
Patients' medical records from 2010-2020 were extracted using billing information of the national health insurance fund of Estonia and ICD-10 codes (pregnancy, appendicitis).
Collected data was stored on RedCap electronic database and analyzed with R Studio.
Two group of patients were compared: pregnant patients who had laparoscopic appendectomy and pregnant patients who had open appendectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pregnant patients who underwent laparoscopic appendectomy | Pregnant patients who underwent laparoscopic appendectomy |
| |
| Pregnant patients who underwent open appendectomy | Pregnant patients who underwent open appendectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Appendectomy | Procedure | Appendectomy - laparoscopic or open |
|
| Measure | Description | Time Frame |
|---|---|---|
| Obstetrical outcomes | Pregnancy loss (fetal demise) - rate of cessation of pregnancy before scheduled delivery | Pregnancy loss within 9 months from appendectomy |
| Measure | Description | Time Frame |
|---|---|---|
| Surgical outcomes | Surgical complications - rate of infectious complications within 30 days after appendectomy | 30 days after appendectomy |
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Inclusion Criteria:
Women with confirmed pregnancy who underwent appendectomy for acute appendicitis.
Exclusion Criteria:
Women who were not pregnant when having an appendectomy
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Study population consists of pregnant women who were pregnant during appendectomy confirmed either before or after the surgical procedure. The population was derived from the billing information from years 2010-2020 of the national health insurance fund of Estonia.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| North Estonia Medical Centre | Tallinn | Estonia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31023289 | Background | Lee SH, Lee JY, Choi YY, Lee JG. Laparoscopic appendectomy versus open appendectomy for suspected appendicitis during pregnancy: a systematic review and updated meta-analysis. BMC Surg. 2019 Apr 25;19(1):41. doi: 10.1186/s12893-019-0505-9. | |
| 29656140 | Background | Prodromidou A, Machairas N, Kostakis ID, Molmenti E, Spartalis E, Kakkos A, Lainas GT, Sotiropoulos GC. Outcomes after open and laparoscopic appendectomy during pregnancy: A meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2018 Jun;225:40-50. doi: 10.1016/j.ejogrb.2018.04.010. Epub 2018 Apr 9. |
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| ID | Term |
|---|---|
| D001064 | Appendicitis |
| ID | Term |
|---|---|
| D059413 | Intraabdominal Infections |
| D007239 | Infections |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
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| ID | Term |
|---|---|
| D001062 | Appendectomy |
| ID | Term |
|---|---|
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| 33935257 | Background | Zeng Q, Aierken A, Gu SS, Yao G, Apaer S, Anweier N, Wu J, Zhao JM, Li T, Tuxun T. Laparoscopic Versus Open Appendectomy for Appendicitis in Pregnancy: Systematic Review and Meta-Analysis. Surg Laparosc Endosc Percutan Tech. 2021 May 3;31(5):637-644. doi: 10.1097/SLE.0000000000000943. |
| D004066 |
| Digestive System Diseases |
| D002429 | Cecal Diseases |
| D007410 | Intestinal Diseases |