Intravenous Iron Supplement to Prevent Postoperative Delirium After Hip Fracture Surgery

Intravenous Iron Supplement to Prevent Postoperative Delirium After Hip Fracture Surgery

This is a clinical trial to evaluate the effect of intravenous iron supplement with Ferinject (Ferric Carboxymaltose) in preventing postoperative delirium after hip fracture surgery.

We hypothesized that IV iron supplement will (1) decrease postoperative delirium in hip fracture patients and (2) decrease the amount of transfusion and transfusion-related complications.

Inclusion Criteria:

• femur neck fracture, intertrochanteric fractures
• Iron deficiency anemia (Hb<12 in women, Hb<13 in men)
• Iron deficiency (Serum ferritin <100ug/L or transferrin saturation<20%)
• Who understands this clinical trial and volunteers and agrees to this trial

Exclusion Criteria:

• Patient under the age of 65 years
• Hb<7 or someone who has acute symptom of anemia(tachycardia, dyspnea, or dizziness)
• High energy trauma
• Preoperative delirium
• MMSE<10
• Underlying disease which involves cognitive dysfunction (e.g. neurovascular diseases, acute myocardial infarction, pulmonary embolism)
• Those who are inappropriate to participate in the clinical trial assessed by the investigators