Role of Immunoscore® in Stage II-III Colorectal Cancer

Role of Immunoscore® in Stage II-III Colorectal Cancer

The proposed study is a bidirectional analytical study, composed of a retrospective and a prospective cohorts. Patients with stage II - III colorectal cancer undergoing oncological surgery will be analyzed. The study will include a convenience sample of 100 individuals. Fifty cases will be included retrospectively and fifty prospectively.

The study aims to evaluate the benefit of using the Immunoscore test as a predictor of recurrence in patients with operated stage II-III colon tumors. It will also be evaluated the impact on oncologic decision and costs.

Inclusion Criteria:

1. Anatomopathological diagnosis of colorectal adenocarcinoma
2. Stage II - III (AJCC 8th edition)
3. Patient undergoing surgery with curative intent

Exclusion Criteria:

1. Current or previous diagnosis (within the last 5 years) of another invasive primary malignant neoplasm, with the exception of non-melanoma skin neoplasm
2. Presence of distant metastatic disease evidenced in imaging tests