Chitosan Versus Glucosamine Phonophoresis in the Management of Knee Osteoarthritis

Chitosan Versus Glucosamine Phonophoresis in the Management of Knee Osteoarthritis: A Randomized Controlled Trial

The study will be conducted to answer the following questions:

• Is there an effect of phonophoresis using glucosamine on pain level , function and range of motion in knee osteoarthritis patients ?
• Is there an effect of phonophoresis using chitosan on pain level , function and range of motion in knee osteoarthritis patients ?
• Is there a difference between the effect of phonophoresis using glucosamine and phonophoresis using chitosan on pain level , function and range of motion in knee osteoarthritis patients ?

Inclusion Criteria:

• unilateral or bilateral grade II knee osteoarthritis (clinical and imaging diagnosis X-ray).
• knee pain intensity ≥ 5 on the Visual Analogue Scale (VAS)

Exclusion Criteria:

• Anterior Cruciate Ligament (ACL) and meniscus injury
• use of oral or injected corticosteroids in the last 3 months
• history of knee surgery or fracture
• acute infectious synovitis or arthritis conditions
• presence of malignancy
• individuals with, topical lesions, contact dermatitis and history of cutaneous hypersensitivity