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Primary objective of this study is to evaluate and compare the measurements of two different optical biometrics systems in patients who will undergo cataract surgery or presbyopia surgery using intraocular lenses (IOL-PC).
This is a prospective study including patients visiting the outpatient Ophthalmology clinic of the University General Hospital of Alexandroupolis, who suffer from diagnosed cataract or presbyopia and are going to undergo implantation of intraocular lenses surgery. The patients will be fully informed about the procedure and the purpose of the study and a written informed consent will be provided by all participants. They will then undergo an ocular biometry examination using two optical biometric systems, Argos (Alcon Laboratories, Inc.) and IOLMaster 500 (Carl Zeiss Meditec AG). IOL Master 500 (Carl Zeiss Meditec AG) is a non-invasive optical biometer that uses partial coherence interferometry (PCI) with a wavelength of 780 nm to measure the AL of the eye. Argos (Alcon Laboratories, Inc.) is a novel non-invasive optical biometer that uses swept source optical coherence tomography (SS-OCT) with a wavelength of 1050 nm. The measurements of the two systems that will be compared are the axial length, the keratometry values, the anterior chamber depth (ACD), the horizontal corneal diameter (white to white [WTW]) and the lens power in diopters (D).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study Group | 100 patients with diagnosed cataract or presbyopia who will undergo implantation of intraocular lenses surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Argos (Alcon Laboratories, Inc.) | Device | An ocular biometry examination will be performed on the affected eyes using the Argos device. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Axial length | The measurement of the axial length of the affected eye using both devices | 1 week |
| Keratometry values | The measurement of keratometry values K1: flat meridian of the anterior corneal surface and K2: steep meridian of the anterior corneal surface of the affected eye using both devices. | 1 week |
| Lens power (D) | The power of the lens is calculated by each device as a function of biometric measurements | 1 week |
| Measure | Description | Time Frame |
|---|---|---|
| Anterior chamber depth (ACD) | The measurement of the anterior chamber depth (ACD) of the affected eye using both devices. | 1 week |
| Horizontal corneal diameter (white to white [WTW]) | The measurement of the horizontal corneal diameter of the affected eye using both devices. |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients with cataract and/or presbyopia.
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| Name | Affiliation | Role |
|---|---|---|
| Georgios Labiris, MD, PhD | Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Ophthalmology, University Hospital of Alexandroupolis | Alexandroupoli | Evros | 68100 | Greece |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40507667 | Result | Panagiotopoulou EK, Polychroniadis T, Bakirtzis M, Tsinopoulos I, Ziakas N, Labiris G. Level of Agreement of Intraocular Lens Power Measurements Between a Swept-Source OCT Biometer and a Partial Coherence Interferometer. J Clin Med. 2025 Jun 2;14(11):3903. doi: 10.3390/jcm14113903. |
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| ID | Term |
|---|---|
| D002386 | Cataract |
| D011305 | Presbyopia |
| ID | Term |
|---|---|
| D007905 | Lens Diseases |
| D005128 | Eye Diseases |
| D012030 | Refractive Errors |
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| IOLMaster 500 (Carl Zeiss Meditec AG) | Device | An ocular biometry examination will be performed on the affected eyes using the IOL Master 500 device. |
|
| 1 week |