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| Name | Class |
|---|---|
| National Institutes of Health (NIH) | NIH |
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The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy Somali Americans | Somali Americans with no known history of hypertension, diabetes, or sleep disorders will have a 24 hour blood pressure monitoring and polysomnography. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 24 hour blood pressure (BP) monitoring | Diagnostic Test | 24-hour ambulatory BP measuring device and blood pressures will be measured every 20 minutes to half hour |
|
| Measure | Description | Time Frame |
|---|---|---|
| Undiagnosed sleep deficiency-short sleep | Number of subjects to have short sleep (<6 hours) as measured by the sleep study | 1 night sleep study, approximately 8-9 hours |
| Undiagnosed sleep deficiency-insomnia | Number of subjects to have insomnia as measured by the sleep study | 1 night sleep study, approximately 8-9 hours |
| Undiagnosed sleep deficiency-obstructive sleep apnea (OSA) | Number of subjects to have OSA as measured by the sleep study | 1 night sleep study, approximately 8-9 hours |
| Disrupted sleep | Number of subjects to have disrupted sleep as measured by the sleep study | 1 night sleep study, approximately 8-9 hours |
| Blood pressure (BP) during wakefulness | Average BP as measured by 24 hour BP monitoring, reported in mmHg | Day 2 |
| Blood pressure (BP) during sleep | Average BP as measured by 24 hour BP monitoring, reported in mmHg | Day 2 |
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Inclusion Criteria:
Exclusion Criteria:
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The research team will partner with Somali operated community-based health clinics, faith-based establishments, community organizations, charter schools and other educational/community centers. In addition, the research team will partner with the Somali Health Advisory Committee (SHAC), a community advisory board based in Rochester and Minneapolis/St. Paul and the Somali Community Resettlement Agency (SCRS) and Somali American Social Services Association (SASSA), two community organizations aimed at integrating Somali immigrants to the United States.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Somers CPL Lab | Contact | 507-422-3499 | CPLSOMALI@mayo.edu |
| Name | Affiliation | Role |
|---|---|---|
| Virend Somers, MD | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic in Rochester | Recruiting | Rochester | Minnesota | 55905 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40088388 | Derived | Greenlund IM, Bock JM, Govindan N, Kantas D, Singh P, Covassin N, Somers VK. Blood Pressure and Heart Rate Response to Orthostasis in Somali Americans. J Racial Ethn Health Disparities. 2026 Jun;13(3):1961-1966. doi: 10.1007/s40615-025-02389-7. Epub 2025 Mar 15. | |
| 39502777 | Derived | Greenlund I, Bock J, Govindan N, Kantas D, Singh P, Covassin N, Somers V. Blood Pressure and Heart Rate Response to Orthostasis in Somali Americans. Res Sq [Preprint]. 2024 Oct 21:rs.3.rs-4925722. doi: 10.21203/rs.3.rs-4925722/v1. |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| D012893 | Sleep Wake Disorders |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D009422 | Nervous System Diseases |
| D009461 | Neurologic Manifestations |
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| ID | Term |
|---|---|
| D001794 | Blood Pressure |
| D017286 | Polysomnography |
| ID | Term |
|---|---|
| D055986 | Vital Signs |
| D010808 | Physical Examination |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| Polysomnography | Diagnostic Test | Measurements will include electroencephalogram, electromyogram, electrooculogram, electrocardiogram, breathing patterns of chest and abdomen, nasal and oral airflow and oxygen saturation. Sleep stages and apneas will be scored in accordance with validated American Academy of Sleep Medicine standards. |
|
|
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001523 | Mental Disorders |
| D006439 |
| Hemodynamics |
| D002320 | Cardiovascular Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |
| D008991 | Monitoring, Physiologic |