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The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) in patients undergoing cesarean section.
This study was designed to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord NLR, PLR and MPV in patients undergoing cesarean section.
The primary endpoint was to compare the effects of general and spinal anesthesia on umbilical cord NLR. Secondary endpoints were determined the general and spinal anesthesia on routine umbilical cord PLR, MPV and newborn Apgar scores at 1st and 5th min.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| General anesthesia group | Evaluate the effects of general anesthesia on NLR, PLR and MPV in patients undergoing cesarean section. |
| |
| Spinal anesthesia group | Evaluate the effects of spinal anesthesia on NLR, PLR and MPV in patients undergoing cesarean section. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| General anesthesia | Other | Evaluate the effects of general anesthesia on NLR, PLR and MPV in patients undergoing cesarean section. |
|
| Measure | Description | Time Frame |
|---|---|---|
| neutrophil-to-lymphocyte ratio | Evaluate the effects of NLR in patients undergoing cesarean section | within 5 minute, following delivery |
| Measure | Description | Time Frame |
|---|---|---|
| platelet-to-lymphocyte ratio | Evaluate the effects of PLR in patients undergoing cesarean section | within 5 minute, following delivery |
| mean platelet volume | Evaluate the effects of MPV in patients undergoing cesarean section |
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Inclusion Criteria:
Exclusion Criteria:
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elective ceserean surgery
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| Name | Affiliation | Role |
|---|---|---|
| Kerem İnanoğlu | Antalya TRH | Principal Investigator |
| Esra Bağ | Antalya TRH | Principal Investigator |
| Arzu Karaveli | Antalya TRH | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Antalya Training and Research Hospital, Department of Anesthesiology and Reanimation | Antalya | 07100 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D000768 | Anesthesia, General |
| D000775 | Anesthesia, Spinal |
| ID | Term |
|---|---|
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
| D000765 | Anesthesia, Conduction |
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| Spinal anesthesia | Other | Evaluate the effects of spinal anesthesia on NLR, PLR and MPV in patients undergoing cesarean section. |
|
| within 5 minute, following delivery |
| Newborn Apgar score 1st minute | Appearance (skin color), Pulse (heart rate), Grimace (reflex irritability), Activity (tone), Respiration. Apgar score at 1st min (0-3: severely depressed, 4-6: moderately depressed, 7-10: excellent condition) | 1st minute after birth |
| Newborn Apgar score 5th minute | Appearance (skin color), Pulse (heart rate), Grimace (reflex irritability), Activity (tone), Respiration. Apgar score at 1st min (0-3: severely depressed, 4-6: moderately depressed, 7-10: excellent condition) | 5th minute after birth |