The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio

Comparison of the Effect of General and Spinal Anesthesia on Umbilical Neutrophil-to-lymphocyte Ratio, Platelet-to-lymphocyte Ratio and Mean Platelet Volume in Patients Undergoing Cesarean Section

The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) in patients undergoing cesarean section.

This study was designed to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord NLR, PLR and MPV in patients undergoing cesarean section.

The primary endpoint was to compare the effects of general and spinal anesthesia on umbilical cord NLR. Secondary endpoints were determined the general and spinal anesthesia on routine umbilical cord PLR, MPV and newborn Apgar scores at 1st and 5th min.

Inclusion Criteria:

• 18 - 45 years
• American Society of Anesthesiology (ASA) II-III
• elective ceserean surgery

Exclusion Criteria:

• declining to give written informed consent
• under 18 years of age or over 45 years of age
• factors affecting NLR, PLR and MPV such as preeclampsia, HELLP syndrome or premature rupture of membranes
• history of neurological and/or neuromucular disease
• cooperation cannot be established
• emergency surgery