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Autogenous bone, with its osteogenic, osteoinductive, and osteo-conductive characteristics has been used for bone grafts with optimal integration into host tissues. For this reason, autogenous bone has been often considered the gold standard of bone regeneration material. However, the amount of autogenous bone that may be harvested is limited, and the harvesting procedure is traumatic.
Bone substitutes, including allografts, xenografts, and alloplasts have been used successfully as alternatives to autogenous bone grafts in ridge augmentation procedures.
In 2008, autogenous tooth bone graft (ATG) was introduced and used for the first time as a bone grafting material for GBR. The tooth contents are extremely similar to that of the alveolar bone. The enamel inorganic, organic, and water contents are 95 percent, 0.6 percent, and 4 percent, respectively. However, in the dentin, the percentages are 70 to 75 percent, 20 percent, and 10 percent, respectively. They are 65 percent, 25 percent, and 10 percent, respectively, when compared to the alveolar bone content.
The aim of this study is to compare ridge augmentation using autogenous bone block (ABB) with immediate implant placement and filling the generated gap with autogenous bone graft (ABG) or ATG, or ridge augmentation using xenograft bone block (XBB) with immediate implant placement and filling the generated gap with ATG.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ABB and ATG with simultaneous implant placement | Experimental | Using ABB with ATG to fill the gap around simultaneously placed dental implants |
|
| XBB and ATG with simultaneous implant placement | Experimental | Using XBB with ATG to fill the gap around simultaneously placed dental implants |
|
| ABB and ABG with immediate implant | Active Comparator | Using ABB with ABG to fill the gap around immediately placed dental implants |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ABB and ATG with simultaneous implant placement | Procedure | Ridge augmentation using ABB and ATG as a graft material with simultaneous implant placement |
|
| Measure | Description | Time Frame |
|---|---|---|
| Clinical evaluation probing pocket depth and amount of bone around simultaneously placed dental implants | Changes on pocket depth and amount of bone using ABG or ATG with ABB or XBB around simultaneously placed dental implants | 9 months |
| radiographic outcome measuring the amount of bone around simultaneously placed dental implants | the radiographic outcome by measuring the amount of bone by using ATG or ABG on bone formation with ABB or XBB around simultaneously placed dental implants | 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dalia R Issa, PhD | Kafrelsheikh University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry, Kafrelsheikh University | Kafr ash Shaykh | 33511 | Egypt |
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| XBB and ATG with simultaneous implant placement | Procedure | Ridge augmentation using XBB and ATG as a graft material with simultaneous implant placement |
|
| ABB and ABG with simultaneous implant placement | Procedure | Ridge augmentation using ABB and ABG as a graft material with simultaneous implant placement |
|
| ID | Term |
|---|---|
| D001784 | Blood Gas Analysis |
| ID | Term |
|---|---|
| D001774 | Blood Chemical Analysis |
| D019963 | Clinical Chemistry Tests |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D012129 | Respiratory Function Tests |
| D003948 | Diagnostic Techniques, Respiratory System |
| D008919 | Investigative Techniques |
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