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Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision. Therefore adequate analgesia is important for recovery.
Erector Spinae Plane Block (ESPB) is a safe anesthesia technique used to provide postoperative analgesia. This study aimed to compare the novel ultrasound-guided ESPB technique with controls in terms of postoperative opioid consumption and postoperative pain control on donor patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Erector Spinae Plane Block | Active Comparator | Erector Spinae Plane Block for Postoperative Analgesia |
|
| Control group | Active Comparator | No regional anesthesia technique will be applied to the control group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Erector Spinae Plane Block | Procedure | Intravenous fentanyl patient control device 48-hour fentanyl consumption will be recorded. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Opioid consumption | The amount of fentanyl required by the patient and given by the device will be recorded for the first 48 hours. | Change from baseline opioid consumption at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Scale | Pain of patients will be evaluated and recorded according to the Visual Analog Scale. | Change from baseline pain scores at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Tumay Uludag Yanaral | Medipol University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul Medipol University Hospital | Istanbul | 34070 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30477577 | Background | Dewe G, Steyaert A, De Kock M, Lois F, Reding R, Forget P. Pain management in living related adult donor hepatectomy: feasibility of an evidence-based protocol in 100 consecutive donors. BMC Res Notes. 2018 Nov 26;11(1):834. doi: 10.1186/s13104-018-3941-1. | |
| 17394151 | Background | Chhibber A, Dziak J, Kolano J, Norton JR, Lustik S. Anesthesia care for adult live donor hepatectomy: our experiences with 100 cases. Liver Transpl. 2007 Apr;13(4):537-42. doi: 10.1002/lt.21074. |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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There are two model for this study. The first group is erector spinae plane block group. The second one is control group.
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The patient and the anesthesiologist who performs postoperative pain evaluation will not know the group.
| Intravenous fentanyl patient control device | Procedure | Intravenous fentanyl patient control device 48-hour fentanyl consumption will be recorded. |
|
| 30292068 | Background | Tsui BCH, Fonseca A, Munshey F, McFadyen G, Caruso TJ. The erector spinae plane (ESP) block: A pooled review of 242 cases. J Clin Anesth. 2019 Mar;53:29-34. doi: 10.1016/j.jclinane.2018.09.036. Epub 2018 Oct 3. |
| 28188611 | Background | El-Boghdadly K, Pawa A. The erector spinae plane block: plane and simple. Anaesthesia. 2017 Apr;72(4):434-438. doi: 10.1111/anae.13830. Epub 2017 Feb 11. No abstract available. |
| 29883965 | Background | Hacibeyoglu G, Topal A, Arican S, Kilicaslan A, Tekin A, Uzun ST. USG guided bilateral erector spinae plane block is an effective and safe postoperative analgesia method for living donor liver transplantation. J Clin Anesth. 2018 Sep;49:36-37. doi: 10.1016/j.jclinane.2018.06.003. Epub 2018 Jun 5. No abstract available. |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |